摘要
慢性阻塞性肺疾病(COPD)是一种以持续气流受限为主要特征的慢性呼吸系统疾病。近年来随着空气污染加重、吸烟人数增多,COPD患病率及病死率呈逐年增长趋势,已成为严重的公共卫生问题之一。既往研究表明,COPD患者除肺部炎性表现外,还伴有心血管疾病(CVD)等肺外严重病变。动脉粥样硬化是CVD的主要病理基础,近年来已成为COPD并CVD研究领域的热点。本研究旨在综述COPD与颈动脉粥样硬化的共同危险因素及发病机制,以期为降低COPD患者CVD发生风险提供参考。
Chronic obstructive pulmonary disease(COPD)is one kind of chronic respiratory disease,which mainly performed as continuous airflow limitation. In recent years,morbidity and mortality of COPD showed a rising tendency year by year as the worsening air pollution and increased smokers,which becomes one of serious public health problems at present. Previous studies showed that,COPD patients usually complicated with severe extrapulmonary disease except for pulmonary inflammatory manifestations,such as cardiovascular disease. Atherosclerosis is the major pathological basis of cardiovascular disease,and it became one of research highlights in COPD combined with cardiovascular disease. This paper received the common risk factors and pathogenesis of COPD and atherosclerosis,to provide a reference for reducing the risk of cardiovascular disease in patients with COPD.
作者
陈丹丹
杨中卫
CHEN Dandan;YANG Zhongwei(Department of Respiratory and Critical Care Medicine,Dongfeng Hospital Affiliated to Hubei University of Medicine, Shiyan 442008,China)
出处
《实用心脑肺血管病杂志》
2019年第1期116-120,共5页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
肺疾病
慢性阻塞性
动脉粥样硬化
危险因素
发病机制
综述
Pulmonary disease,chronic obstructive
Atherosclerosis
Risk factors
Pathogenesis
Review
