摘要
目的探讨老年患者代谢综合征不同组合成份与颈动脉内膜中层厚度的关系。方法选择老年代谢综合征患者79例、年龄60岁以上,按组成成份不同分为老年伴糖尿病组41例,老年非糖尿病组38例,同时选年龄<60岁年轻伴糖尿病组37例。用彩色多普勒超声心动图仪检测颈动脉内膜中层厚度。结果老年伴糖尿病组与老年非糖尿病组颈动脉内膜中层厚度均较年轻伴糖尿病组明显增厚,二者之间有统计学意义(P<0.01),而老年伴糖尿病组又较老年非糖尿病组增厚明显,二组统计有显著意义(P<0.05)。相关分析显示颈动脉内膜-中膜厚度与年龄(r=0.300,P<0.01)、高血压病程(r=0.255,P<0.01)呈显著正相关,斑块发生率以老年伴糖尿病组最高(73.2%),其次为老年非糖尿病组(50%),年轻伴糖尿病组最少(21.6%)三组差异有显著性(P<0.05和0.01)。结论合并糖尿病的代谢综合征患者颈动脉内膜中层厚度较非糖尿病代谢综合征患者明显增厚,老年代谢综合征患者的颈动脉内膜-中膜厚度又较非老年患者增厚明显。
Aim To explore the relationship between different components of metabolic syndrome and carotid intima-media thickness. Methods 79 eider metabolic syndrome patients （mere than 60 years old） were divided into two groups according to the different components of metabolic syndrome;41 patients with diabetes mellitus and 38 patient without diabetes mellitus. Meanwhile,37 patients with diabetes mellitus is younger than 60 years old . Carotid intima-media thickness was measured by Doppler ultrasonography. Results Carotid artery intima-media thickness in elderly patients are significantly thicker than that of younger ones（ P 〈 0. 001 ）, while intima-media thickness combining with diabetes mellitus are significantly thicker than that without diabetes mellitus in elderly patients （P 〈 0.05）. By correlation analysis, the carotid artery intima-media thickness was positively correlated with age （r=0.300, P〈0.001）, duration of hypertension （r=0.255, P〈0.001）. The oeeurrenees of plaque are highest in dderly patients with diabetes mellitus （73.2%）, secondly in dderly patients without diabetes mellitus（50% ） and lowest in younger patients with diabetes mellitus （21.6%）, Statistical analysis is positive （ P 〈 0.05 and 0. 001 ）. Condusion Intima-media thickness combining with diabetes mellitus are significantly thicker than that no diabetes mellitus in metabolic syndrome in elderly patients. Elder metabolic syndrome patients have higher carotid intima-media thickness than younger ones.
出处
《中国动脉硬化杂志》
CAS
CSCD
2006年第7期617-619,共3页
Chinese Journal of Arteriosclerosis
