摘要
目的研究五类水果与膀胱癌发病率的关系。方法 2005年9月～2012年6月,采用多中心病例对照研究方法,在广州市第一人民医院、中南大学附属第二医院、华中科技大学同济医学院附属同济医院、浙江大学附属第一医院共招募432例膀胱癌患者和392例非膀胱癌患者,将膀胱癌患者作为实验组,非膀胱癌患者作为对照组,分别对两组患者进行问卷调查,收集数据后进行统计分析。结果实验组问卷应答率及问卷有效率分别为99.1%、100.0%,对照组问卷应答率及问卷有效率分别为99.5%、100.0%;食用柑橘类水果≥2次/周或可显著降低膀胱癌的发病风险(P <0.05)。结论多食用柑橘类水果或许有助于降低膀胱癌发生的风险。
Objective To study the relationship between five kinds of fruits and the incidence of bladder cancer. Methods A multicenter case-control study was conducted from September 2005 to June 2012. Four hundred and thirty-two cases of bladder cancer and 392 cases of non bladder cancer were recruited in Guangzhou First People′s Hospital, the Second Affiliated Hospital of Central South University, Tongji Hospital Affiliated to Tongji Medical College of Huazhong University of Science and Technology and the First Affiliated Hospital of Zhejiang University. Patients with bladder cancer were classified as experimental group, and non bladder cancer patients were classified as control group. Patients of two groups were investigated and data was collected for statistical analysis. Results The response rate and the effective rate of questionnaire of the experimental group were 99.1% and 100.0%, and those of the control group were 99.5% and 100.0% respectively. Eating citrus fruits more than or equal to 2 times per week could significantly reduce the risk of bladder cancer(P < 0.05). Conclusion Eating more citrus fruits may help reduce the risk of bladder cancer.
作者
凌琦
吴永定
秦国强
LING Qi;WU Yongding;QIN Guoqiang(Administrative Office, Guangzhou Hospital of Integrated Chinese and Western Medicine, Guangdong Province, Guangzhou 510800, China;Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People′s Hospital the Second Affiliated Hospital of South China University of Technology, Guangdong Province, Guangzhou 510180, China;Department of Urology, Guangzhou Panyu Central Hospital, Guangdong Province, Guangzhou 511400, China)
出处
《中国医药导报》
CAS
2019年第6期45-48,共4页
China Medical Herald
关键词
膀胱癌
发病率
病例对照研究
Bladder cancer
Incidence
Case-control study
