摘要
目的探讨地佐辛不同给药方式对芬太尼复合麻醉术后苏醒期拔管及镇痛镇静效果的影响。方法选取本院2016年1月至2017年12月期间收治的86例腹腔镜手术患者,所有患者均行芬太尼复合麻醉,将所有患者随机分为甲组和乙组,每组43例,甲组手术结束前30 min肌肉注射0.2 mg/kg地佐辛,乙组静脉滴注1μg/kg地佐辛,比较两组术后苏醒时间、气管拔管时间及镇静镇痛效果。结果甲组术后苏醒时间与气管拔管时间均明显短于乙组,两组差异有统计学意义(P<0.05);甲组术后苏醒时VAS镇痛评分与SAS镇静评分略低于乙组,差异无统计学意义(t=1.668/t=0.198,P>0.05);苏醒后1 h、2 h,甲组VAS镇痛评分与SAS镇静评分均明显低于乙组,差异有统计学意义(P<0.05)。结论地佐辛肌肉注射给药方式能够缩短芬太尼复合麻醉术后苏醒及拔管时间,提高镇痛镇静效果,值得临床推广应用。
Objective To explore the effect of different dosing methods of dezocine on extubation, analgesia and sedation during recovery period after fentanyl combined anesthesia. Methods 86 cases of laparoscopic surgery from January 2016 to December 2017 were selected. All patients were treated with fentanyl combined anesthesia. All the patients were randomly divided into group A and group B, each group was divided into 43 cases. The 30 min muscles were injected 0.2 mg/kg dizocin before the end of the operation, and group B intravenous drip 1 g/kg dezocine, two Postoperative recovery time, tracheal extubation time and sedation and analgesia effect were observed. Results The waking time and endotracheal extubation time of group A were significantly shorter than group B, and the difference between the two groups was statistically significant (P<0.05). The VAS analgesic score and the SAS sedative score of group A were slightly lower than those in group B, but the difference was not statistically significant (t=1.668/t=0.198, P >0.05);At 1 h and 2 h after recovery, the VAS analgesia score and SAS sedation score in group A were significantly lower than those in group B (P<0.05). Conclusion The intramuscular injection of dezocine can shorten the waking and extubation time of fentanyl after compound anaesthesia, and improve the analgesic and sedative effect. It is worthy of clinical application.
作者
庄朝华
郭迅
季春华
Zhuang Chaohua;Guo Xun;Ji Chunhua(Tongzhou Hospital of Traditional Chinese Medicine, Nantong, Jiangsu, 226300, China)
出处
《当代医学》
2019年第6期53-55,共3页
Contemporary Medicine
关键词
地佐辛
给药方式
芬太尼复合麻醉
苏醒期拔管
镇痛镇静
Dezocine
Administration mode
Fentanyl combined anesthesia
Extubation during recovery period
Analgesia and sedation
