摘要
目的探讨屈他维林联合托特罗定治疗经尿道前列腺电切术后膀胱痉挛的临床效果。方法随机抽取2016年12月～2018年8月于江西省鹰潭市人民医院铁路分院接受治疗的60例经尿道前列腺电切术后膀胱痉挛患者作为研究对象,随机将其分为治疗组(n=30)与对照组(n=30)。对照组患者给予托特罗定治疗,治疗组患者给予屈他维林联合托特罗定治疗。比较两组患者治疗后的膀胱痉挛次数及持续时间,并比较两组患者治疗前后的膀胱过度活动症评分(OABSS)、膀胱状况感知量表(PPBC)评分、视觉模拟(VAS)评分及生活质量(QOL)评分。结果两组患者治疗后24 h的膀胱痉挛次数及持续时间比较,差异无统计学意义(P>0.05);两组患者治疗后48、72 h的膀胱痉挛次数均少于治疗后24 h,持续时间均短于治疗后24 h,差异有统计学意义(P<0.05);治疗组患者治疗后48、72 h的膀胱痉挛次数均少于对照组,持续时间均短于对照组,差异有统计学意义(P<0.05)。两组患者治疗前的OABSS、PPBC、VAS评分比较,差异无统计学意义(P>0.05);两组患者治疗后的OABSS、PPBC、VAS评分均低于治疗前,差异有统计学意义(P<0.05);治疗组患者治疗后的OABSS、PPBC、VAS评分均低于对照组,差异有统计学意义(P<0.05)。两组患者治疗前的QOL评分比较,差异无统计学意义(P>0.05);两组患者治疗后的QOL评分均高于治疗前,差异有统计学意义(P<0.05);治疗组患者治疗后的QOL评分高于对照组,差异有统计学意义(P<0.05)。结论屈他维林联合托特罗定治疗经尿道前列腺电切术后膀胱痉挛,取得让人满意的效果,临床价值高。
Objective To investigate the clinical effect of Drotaverine combined with Tolterodine in the treatment of bladder spasm after transurethral resection of prostate. Methods Sixty patients with bladder spasm after transurethral resection of the prostate who were treated in Jiangxi Yingtan People′s Hospital Railway Branch from December 2016 to August 2018 were randomly selected as study objects and randomly divided into the treatment group (n=30) and the control group (n=30). The control group was treated with Tolterodine, and the treatment group was treated with Drotaverine combined with Tolterodine. The number and duration time of bladder spasm after treatment were compared between the two groups. The overactive bladder symptom score (OABSS), bladder conditional awareness scale (PPBC) score, visual analogue scale (VAS) score, and quality of life (QOL) before and after treatment were compared between the two groups. Results There were no significant differences in the number and duration time of bladder spasm between the two groups at 24 h after treatment (P>0.05). The number of bladder spasm at 48 and 72 h after treatment in the two groups was fewer than that at 24 h after treatment, the duration time was shorter than that at 24 h after treatment, and the differences were statistically significant (P<0.05). The number of bladder spasm at 48 and 72 h after treatment in the treatment group was fewer than that in the control group, the duration time was shorter than that in the control group, and the differences were statistically significant (P<0.05). There were no significant differences in the scores of OABSS, PPBC and VAS between the two groups before treatment (P>0.05). The scores of OABSS, PPBC and VAS after treatment in the two groups were lower than those before treatment, and the differences were statistically significant (P<0.05). The scores of OABSS, PPBC and VAS after treatment in the treatment group were lower than those in the control group, and the differences were statistically significant (P<0.05).
作者
洪波
洪燕
庄娟
HONG Bo;HONG Yan;ZHUANG Juan(Yingtan People′s Hospital Railway Branch, Jiangxi Province, Yingtan 335000, China;Fuzhou Dongxiang District People′s Hospital, Jiangxi Province, Fuzhou, 331800, China;Jiangxi Provincial People′s Hospital Railway Branch, Yingtan 335000, China)
出处
《中国当代医药》
2019年第4期114-117,共4页
China Modern Medicine
