摘要
目的:探讨卵巢过度刺激综合征(OHSS)高危人群服用陈皮杜仲水对预防OHSS及临床结局的影响。方法:回顾性分析2011年2月-2017年2月在泉州市妇幼保健院生殖医学中心进行IVF/ICSI治疗的98例高危OHSS患者,分为两组。对照组所有患者均于HCG扳击后予以营养宣教,观察组在营养宣教的同时予服用中药(陈皮杜仲水),共用14 d,观察OHSS的发生率及临床结局。结果:对照组的OHSS发生率高于观察组,但无显著意义,其中,对照组中、重度OHSS的发生率显著高于观察组,差异有统计学意义。其临床妊娠率、流产率、畸形率两组比较差异均无统计学意义。结论:陈皮杜仲水能够显著降低高危OHSS患者中重度OHSS的发生率,对OHSS高危人群鲜胚周期移植患者使用陈皮杜仲水是安全有效的。
Objective:To investigate the effect of the treatment of Chenpi Duzhong decoction(陈皮杜仲水)on the prevention of OHSS and the clinical outcome.Methods:98 patients with high risk OHSS were enrolled in IVF/ICSI treatment in the center of reproductive medicine of the Maternal and Child Health Center of Quanzhou City from February 2011 to February 2017.All patients in the control group were given nutritional education after the HCG operation,and the observation group was given Chinese traditional Chinese medicine(Chenpi Duzhong decoction)at the same time of the nutrition education,and the incidence and clinical outcome of OHSS were observed after 14 d.Results:The incidence rate of OHSS in the control group was higher than that in the observation group,but there was no significant significance.Among them,the incidence rate of moderate and severe OHSS of the control group was significantly higher than that of the observation group.There was no statistically significant difference between the two groups of pregnancy rate,flow rate and abnormality rate.Conclusion:Chenpi Duzhong decoction(陈皮杜仲水)could significantly reduce the incidence of severe OHSS in highrisk OHSS patients,and it was safe and effective for patients with high risk during the in vitro fertilization-embryo transferring.
出处
《中医临床研究》
2018年第36期66-68,共3页
Clinical Journal Of Chinese Medicine
关键词
陈皮杜仲水
卵巢过度刺激综合征
体外受精-胚胎移植
Chenpi Duzhong decoction
Ovarian hyperstimulation syndrome
In vitro fertilization-embryo transfer