摘要
卵巢过度刺激综合征为多发生于辅助生殖技术促排卵后黄体阶段或妊娠早期的医源性并发症之一,其主要病理特征是卵巢增大、全身毛细血管增生和通透性体液渗出、血液浓缩、水电解质平衡失调,常见于多囊卵巢综合征患者。连方教授认为卵巢过度刺激综合征的中医病机是脾肾两虚、水饮停聚,进而影响气血运行可出现气滞血瘀痰阻等病理变化,为本虚标实之证,与脾肾关系密切,可涉及心、肝、肺三脏。其中医治疗以温阳健脾、利水行气为主,佐以活血化瘀,方用参苓白术散合二仙调经方加减;西医治疗应注意及时补充体液以纠正低血容量状态,同时维持水电解质酸碱平衡及血浆胶体渗透压,防止出现肝肾功能障碍、循环衰竭、血栓形成等一系列并发症。连方教授总结多年的临床经验,往往根据患者的个体情况从中西医结合角度预防治疗本病,标本兼顾、病证结合,多能取得显著的临床疗效。
Ovarian hyperstimulation syndrome is one of the most common iatrogenic complications in the luteal phase or early pregnancy after assisted reproductive technology.Its main pathological features are ovarian enlargement,systemic capillary hyperplasia and permeability fluid exudation,blood concentration,and imbalance of water and electrolyte balance,often seen in patients with polycystic ovary syndrome.Professor LIAN Fang believes that the pathogenesis of ovarian hyperstimulation syndrome is caused by deficiency of spleen and kidney,water and body fluid retention,and then affects the movement of Qi and blood,which can lead to pathological changes such as Qi stagnation,blood stasis and phlegm obstruction.Among them,the main medical treatment is warming Yang and invigorating spleen,promoting water and Qi,promoting blood circulation and removing blood stasis,Shenling Baizhu Powder(参苓白术散)and Erxian Tiaojing Formula(二仙调经方)are the main prescriptions.In the treatment of Western medicine,we should pay attention to timely supplement body fluid to correct the state of low blood volume,maintain the acid-base balance of water and electrolyte and plasma colloid osmotic pressure,and prevent a series of complications such as liver and kidney dysfunction,circulatory failure and thrombosis.Based on many years of clinical experience,Professor LIAN Fang often prevents and treats the disease from the perspective of integrated traditional Chinese and Western medicine according to the individual situation of patients.Taking into account both specimens and disease syndromes,the treatment can achieve significant clinical efficacy.
作者
董丽
连方
吴海萃
辛欣
DONG Li;LIAN Fang;WU Haicui;XIN Xin(Shandong University of Traditional Chinese Medicine,Jinan 250014,Shandong,China;Affiliated Hospital of Shandong University of Traditional Chinese Medicine,Jinan 250011,Shandong,China)
出处
《辽宁中医杂志》
CAS
2022年第2期21-24,共4页
Liaoning Journal of Traditional Chinese Medicine
基金
国家自然科学基金(81774355,81974577,81703958)
山东省重大科技创新工程项目(2018CXGC1302)
山东省重点研发计划(2019GSF108067)
关键词
卵巢过度刺激综合征
脾肾两虚
温阳健脾
行气利水
连方
名医经验
ovarian hyperstimulation syndrome
deficiency of spleen and kidney
warming Yang and invigorating spleen
promoting Qi and water
LIAN Fang
experience of famous doctors
