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床旁支气管肺泡灌洗联合病原学检测在呼吸机相关性肺炎诊治中的应用效果观察 被引量:17

Effect of Bedside Bronchoalveolar Lavage Combined with Etiological Examination in Diagnosis and Treatment of Patients with Ventilator-associated Pneumonia
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摘要 目的探讨床旁支气管肺泡灌洗联合病原学检测在呼吸机相关性肺炎(VAP)诊断和治疗中的应用效果。方法选取2017年2月—2018年5月收治的VAP患者130例,按照治疗方法分为观察组和对照组,每组65例。2组均给予常规治疗,观察组给予床旁纤维支气管镜肺泡灌洗,对照组给予常规吸痰处理。对比2组临床疗效、肺部感染评分(CPIS)、呼吸动力学指标。结果观察组有效率均高于对照组(P <0. 05)。2组干预后CPIS和呼吸动力学指标均低于干预前,且观察组低于对照组(P <0. 05)。结论床旁支气管肺泡灌洗联合病原学检测临床效果更好,对患者肺部感染控制及呼吸动力学恢复疗效显著。 Objective To investigate effect of bedside bronchoalveolar lavage combined with etiological examination in diagnosis and treatment of patients with ventilator-associated pneumonia(VAP).Methods A total of 130 VAP patients admitted during February 2017 and May 2018 were divided into observation group and control group(n=65 in each group)according to therapeutic methods.All patients had received conventional therapy.Observation group was given bronchoalveolar lavage through bedside fiberoptic bronchoscope,while control group was treated with conventional aspiration of sputum.Values of curative effect,clinical pulmonary infection score(CPIS)and pneodynamics indexes were compared between two groups.Results Value of effective rate in observation group was significantly higher than that in control group(P<0.05).After intervention,values of CPIS scores and pneodynamics indexes were significantly lower than those before intervention in two groups,and the values in observation group were significantly lower than those in control group(P<0.05).Conclusion Bedside bronchoalveolar lavage combined with etiological examination may achieve better therapeutic effect.It has significant effects on controlling pulmonary infection and recovery of respiratory dynamics.
作者 赵志伟 张洋洋 张艳敏 卢秋玲 王玉红 ZHAO Zhi-wei;ZHANG Yang-yang;ZHANG Yan-min;LU Qiu-ling;WANG Yu-hong(Department of Respiratory Medicine,Affiliated Hospital of Chengde Medical College,Chengde,Hebei 067000,China;Department of Tuberculosis,Hebei Chest Hospital,Shijiazhuang 050041,China)
出处 《解放军医药杂志》 CAS 2019年第1期36-39,共4页 Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金 河北省科技计划项目(132777249)
关键词 肺炎 呼吸机相关性 肺部感染 支气管肺泡灌洗 病原学检测 Pneumonia,ventilator-associated Pulmonary infection Bronchoalveolar lavage Etiological examination
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