摘要
目的观察西咪替丁联合双嘧达莫片治疗小儿过敏性紫癜的效果。方法将在2014年1月—2018年1月时间内该院过敏性紫癜患儿98例随机分为治疗组与对照组,对照组给予常规药物治疗,包括葡萄糖酸钙、维生素C、开瑞坦等。治疗组予以西咪替丁+双嘧达莫片治疗。结果治疗组患儿紫癜消失时间(7.96±1.02)d、蛋白尿消失时间(5.60±0.27)d、关节肿痛消失时间(11.96±1.36)d、腹痛消失时间(3.53±0.87)d、IgA(2.40±0.05)g/L、IgM(1.29±0.36)g/L、C3(1.30±0.04)g/L、CRP(0.62±6.49)ng/mL、有效率97.96%,与对照组差异有统计学意义(t=21.048 9,3.310 8,14.340 4,13.654 9,75.236 2,49.435 2,65.785 5,1.147 1,χ~2=4.900 0,P<0.05)。结论将西咪替丁联合双嘧达莫片应用到小儿过敏性紫癜的治疗中,可缩短用药时间,提高治疗有效率。
Objective To observe the effect of cimetidine combined with dipyridamole in the treatment of allergic purpura in children. Methods 98 children with allergic purpura in the hospital from January 2014 to January 2018 were randomly divided into treatment group and control group. The control group received conventional drug treatment, including calcium gluconate, vitamin C, and ceramide. The treatment group was treated with cimetidine + dipyridamole tablets. Results The disappearance time of purpura in children in the treatment group(7.96±1.02)d, the disappearance time of proteinuria (5.60±0.27)d, the disappearance time of joint swelling and pain(11.96±1.36)d, the disappearance time of abdominal pain (3.53±0.87)d, IgA (2.40±0.05)g/L, IgM (1.29±0.36) g/L, C3(1.30±0.04)g/L, CRP (0.62±6.49)ng/mL, and effective rate 97.96%, which was significantly different from the control group (t=21.048 9, 3.310 8, 14.340 4, 13.654 9, 75.236 2, 49.435 2, 65.785 5, 1.147 1,χ^2=4.900 0, P<0.05). Conclusion The application of cimetidine combined with dipyridamole tablets in the treatment of children with allergic purpura can shorten the time of medication and improve the efficiency of treatment.
作者
孙秀芹
SUN Xiu-qin(Department of Pediatrics,Jiangyin Hospital of Traditional Chinese Medicine,Nanjing University of Traditional Chinese Medicine,Wuxi,Jiangsu Province,214400 China)
出处
《系统医学》
2018年第23期86-88,共3页
Systems Medicine
