期刊文献+

系统评价体系探讨微波消融术治疗甲状腺良性结节的临床应用价值 被引量:24

Clinical values of microwave ablation in the treatment of benign thyroid nodules
下载PDF
导出
摘要 目的运用系统评价体系探讨微波消融术治疗甲状腺良性结节的临床应用价值。方法回顾性分析2015年5月至2016年2月期间入住皖北煤电集团总医院并行超声引导下微波消融术治疗甲状腺良性结节的50例病人的资料。术后随访6个月,运用系统评价系统从症状(术中)、术后并发症、实验室检测及彩超检查等多方面评估其治疗效果及术后并发症发生情况,进一步客观、全面明确其临床价值。结果所有病人术中不适主诉发生率低,且均可耐受;术后颈部无疤痕;术后并发症少,1周后均明显恢复,未出现永久性后遗症。与术前甲状腺功能相比,术后3 d游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)明显升高,促甲状腺激素(TSH)明显下降,差异有统计学意义;术后1个月FT3、FT4及TSH均与术前相仿,差异无统计学意义。与术前炎症因子相比,术后第一天C反应蛋白(CRP)、肿瘤坏死因子-α(TNF-α)、白介素-6(IL-6)差异有统计学意义;术后1周,其炎症因子水平均差异无统计学意义。治疗前直径(2. 58±0. 50) cm,结节体积(3. 50±0. 51) cm3;随访6个月后病人的结节直径(0. 65±0. 33) cm,结节体积(0. 37±0. 46) cm3,治疗前后差异有统计学意义(P <0. 05)。病人治疗6月后总有效率达90%,痊愈10%,有效80%,好转10%,失败0%。结论系统评价体系评估超声引导微波消融术治疗甲状腺结节具有创伤小、无疤痕、术后恢复快等优点,具有一定的临床推广意义。 Objective Using the systematic evaluation system to investigate the clinical values of microwave ablation in the treatment of benign thyroid nodules.Methods We retrospective analyzed the clinical data of 50 patients with benign thyroid nodules treated by microwave ablation under the guidance of ultrasound in the Thyroid and Breast Center of our hospital from May-2015 to February-2016.After 6 months'follow-up,evaluation system assessed the therapeutic effection and postoperative complications from the symptoms(intraoperative),postoperative complications,laboratory detections and ultrasound examination,further objectively and comprehensively clarify its clinical values.Results There were low rate of discomfort incidence in all patients,that can be tolerated,with no neck scar.Postoperative complication is low.All patients recoveried in a week.No permanent sequel was found.Compared with the preoperative thyroid function,FT3 and FT4 increased significantly after 3 days,and the TSH decreased significantly.The difference was statistically significant.The FT3,FT4 and TSH were similar to those before surgery,and the difference was not statistically significant.Compared with the preoperative inflammatory factors,there was a statistically significant difference in CRP,IL-6 and TNF-a of the first day postoperative.There was no statistically significant in those factors1 week later.The average diameter of all nodules before treatment is about(2.58±0.50)cm,nodule volume(3.50±0.51)cm^3.After 6 months'follow-up,the average diameter of nodules is about(0.65±0.33)cm,nodule volume(0.37±0.46)cm^3.There were statistically significant differences(P<0.05).After 6 months,the total effective rate was 90%,and the cured rate,effective rate were 10%was and 80%respectively.10%were improved and 0%failed.Conclusion Evaluating by systematic evaluation system,ultrasound guided microwave ablation for the treatment of thyroid nodules has the advantages of less trauma,no scar,faster postoperative recovery,with certain clinical significances.
作者 林宗武 陈洁 马成权 LING Zongwu;CHEN Jie;MA Chenquan(Thyroid and Breast Center of Wanbei Coal-electricity Group General Hospital,Suzhou,Anhui234000,China)
出处 《安徽医药》 CAS 2019年第1期33-36,213,共5页 Anhui Medical and Pharmaceutical Journal
关键词 甲状腺结节 微波 导管消融术 超声检查 治疗结果 Thyroid nodules Microwaves Catheter ablation Ultrasonography Treatment outcome
  • 相关文献

参考文献10

二级参考文献91

  • 1郭乐杭,徐辉雄.超声引导激光消融治疗甲状腺结节的进展[J].中华医学超声杂志(电子版),2013,10(5):360-361. 被引量:9
  • 2彭彩碧,文重远,李竞,史锡腾.射频消融猪甲状腺毁损灶形成的实验研究及意义初探[J].实用医学杂志,2005,21(23):2604-2606. 被引量:20
  • 3曹献廷.手术解剖学[M].北京:人民卫生出版社,1996.832. 被引量:3
  • 4DUPUY DE, MONCHIK JM, DECREA C, et al. Radiofrequency ablation of regional recurrence from well-differentiated thyroid malignancy[J]. Surgery, 2001, 130(6): 971-977. 被引量:1
  • 5JEONG WK, BAEK JH, RHIM H, et al. Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients[J]. Eur Radiol, 2008, 18(12): 1244-1250. 被引量:1
  • 6DUPUY DE, MONCHIK JM, DEEREA C, et al. Radiofequeneyablation of regional reCU1Tellce from well-differentiated thyroid malign ancy[J]. Surgery, 2001, 130: 971-977. 被引量:1
  • 7SMITH S, GILLAMA A. Imaging appearances following thermal ablation[J]. Clinical Radiology, 2008, 63(1): 1-11. 被引量:1
  • 8OKUMA T, OKAMURA T, MATSUOKE T, et al. Fluorine 18 fluorodexyglucose position emission tomography for assessment of patients with unresectable recurrent or metastatic lung cancer af- ter CT-guided radiofrequency ablation preliminary results[J]. Ann Nucl MED, 2006, 20(2): 115-121. 被引量:1
  • 9SAVATEK RS, SIMS R, ANDERSON JK, et al. Magnetic reso- nance imaging characteristics of renal tumors after radiofrequency ablation[J]. Urology, 2006, 67(3): 508-512. 被引量:1
  • 10陈孝平,汪建平.外科学[M].第8版.北京:人民卫生出版社,2013. 被引量:97

共引文献258

同被引文献204

引证文献24

二级引证文献110

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部