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麻杏石甘汤联合克拉霉素对肺炎咳嗽患儿临床研究

Clinical study of Ma Xing Shi Gan Decoction Combined with clarithromycin in children with pneumonia cough
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摘要 目的探讨麻杏石甘汤联合克拉霉素对肺炎咳嗽患儿肺功能及临床症状消失时间的影响。方法选取我院收治的112例肺炎咳嗽患儿随机分为两组,各56例,对照组仅应用克拉霉素治疗,观察组在对照组基础上配合麻杏石甘汤治疗。对比两组临床疗效、症状体征消失时间、肺功能指标。结果观察组总有效率94.64%较对照组75.00%高,差异有统计学意义(P<0.05);观察组退热、咳嗽、肺啰音及X线消失时间均较对照组少,差异有统计学意义(P<0.05);两组治疗后用力肺活量(FVC)、第一秒用力呼气量(FEV1)及最大呼气流速(PEF)明显高于治疗前,差异有统计学意义(P<0.05),且观察组均高于对照组,差异有统计学意义(P<0.05)。结论麻杏石甘汤联合克拉霉素治疗肺炎咳嗽患儿疗效显著,可有效改善患儿临床症状及肺功能指标。 Objective To explore the effects of Maxing Shigan Decoction combined with Clarithromycin on lung function and clinical symptoms disappearance time in children with pneumonia-caused cough.Methods 112 cases of pneumonia and cough were randomly divided into two groups,56 cases in each group.The control group was treated with clarithromycin only.The observation group was treated with the control group on the basis of the Ma Xing Shi Gan Decoction.The clinical efficacy,symptoms and signs disappearance time and lung function indexes of the two groups were compared.Results The total effective rate of the observation group was 94.64%,which was higher than 75.00%of the control group(P<0.05);the fever,cough,lung rale and X-ray disappearance times in the observation group were less than those in the control group(P<0.05);the forced vital capacity(FVC),the forced expiratory volume in first second(FEV1)and the peak expiratory flow(PEF)after treatment in the two groups were significantly higher than those before the treatment(P<0.05),and the observation group were all higher than the control group(P<0.05).Conclusion Maxing Shigan Decoction combined with Clarithromycin in the treatment of pneumonia-caused cough has a remarkable curative effect,it can significantly shorten the disappearance time of clinical symptoms,effectively improve the lung function.
作者 李琦 LI Qi(Yancheng Red Cross Hospital Traditional Chinese Medicine ward,Jiangsu Yancheng 224000,China)
出处 《全科口腔医学电子杂志》 2018年第35期11-12,18,共3页 Electronic Journal of General Stomatology
关键词 麻杏石甘汤 克拉霉素 肺炎咳嗽 肺功能 Maxing Shigan Decoction Clarithromycin Pneumonia-caused cough Lung function
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