摘要
目的分析感染性休克患者早期容量复苏达标后采用限制性液体管理策略对左心室舒张功能的影响。方法将我院收治的99例复苏达标后感染性休克患者随机分为两组,对照组49例予开放性液体管理,观察组50例予限制性液体管理,比较两组液体平衡时间及心肌损伤标志物变化情况。结果观察组液体负平衡时间高于对照组,NT-proBP、cTnI、E/e′、MODS发生率以及病死率均低于对照组(P<0.05)。结论限制性液体管理策略可明显改善感染性休克患者左心舒张功能,减轻心肌损伤,促进患者预后。
Objective To analyze the effect of restrictive fluid management strategy on left ventricular diastolic function in patients with septic shock after early resuscitation of volume recovery.Methods99cases of septic shock were randomly divided into2groups,49cases in the control group were treated with open liquid management,50cases in the observation group were given restrictive liquid management,and the liquid balance time and myocardial damage markers in the two groups were compared.Results The negative balance time of the observation group was higher than that of the control group,and the incidence and mortality of NT-proBP,cTnI,E/e',MODS were lower than those of the control group(P<0.05).Conclusion Restrictive fluid management strategy can prevent the occurrence of left ventricular diastolic dysfunction,reduce myocardial injury and promote the prognosis of patients with septic shock.
作者
杨文典
陈奇
李芝明
YANG Wen-dian;CHEN Qi;LI Zhi-ming(People's Hospital of Zhengzhou,Zhengzhou,Henan,450003,China)
出处
《蛇志》
2018年第4期619-621,共3页
Journal of Snake
关键词
感染性休克
容量复苏
限制性液体管理
左心室舒张功能
septic shock
volume resuscitation
restrictive fluid management
left ventricular diastolic function
