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容量负平衡改善肺癌术后右心功能的研究 被引量:2

Study of control balance on less liquid volume to improve function of right heart after lung cancer operation
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摘要 目的:探讨肺癌切除术后液体输入量和排出量的合理范围及其对右心功能的影响。方法:常规组(术后输入量>排出量)45例,术后以40~50ml/kg输入液体;试验组(输入量<排出量)45例,输液20~25ml/kg,并强化利尿处理。两组术前、后均用彩超测量右心血流动力学参数,监测心功能并比较并发症发生率。结果:常规组术后总液体输入量是平均(2683±246)ml/d,尿(2298±215)ml/d;试验组分别为(1725±212)ml/d,(2860±185)ml/d,P<0.05。心功能监测:常规组:心率(126±27)次/min,收缩压/舒张压(112±23)/(93±8)mmHg,中心静脉压(16±3)cmH2O;试验组分别为(98±16)次/min,(145±18)/(92±7)mmHg,(8+2)cmH2O(P<0.05~<0.01)。右心血流动力学指标:常规组:PASP(肺动脉收缩压)(56.87±9.31)mmHg,PVRI(肺血管阻力指数)23.18±6.22,RVEF(右心室射血分数)0.45±0.03,RVEDVI(右心室舒张末容积指数)51.42±6.37;试验组分别为:(31.17±9.23)mmHg,17.53±5.43,0.55±0.07,45.17±4.71(P<0.05~<0.01)。试验组术后并发症发生率明显低于常规组(P<0.01)。结论:术后常规组总液体输入量>排出量。试验组输入量<排出量,心功和血流动力学状况均优于常规组。肺切除术后容量负平衡对右心功能的改善有显著作用。 Objective: To explore the reasonable limits on volume of infusion and urination and its influence of right heart function after lung cancer operation. Methods: After operation both of groups were compared: clinical routine group (45 cases, infused with volume of 40-50 ml/kg), experimental group (45 cases, infused with volume of 20- 25 ml/kg and forced with diuresis). Parameters of hemodynamics were measured with ultrasonic cardiogram. Results: In routine group, infusion volume was (2683±246) ml/d, urination was (2298±215) ml/d; esperimental group respectively was (1725±212) ml/d and (2860±185) ml/d after operation (P〈0.05). The heart rate was (126±27) time/rain, systolic blood pressure/diastolic blood pressure was (122± 23) / (93± 8) mmHg, central venous pressure (CVP) was (16±3) cm H2O in routine group and those of experimental group were HR (98±16) time/rain, SBP/DBP (145±18) / (92±7) mmHg, CVP (8±2) cm H2O in 3 days post operation. In 7 days post operation the pulmonary artery systolic pressure (PASP) was (56.87± 9.31) mmHg, pulmonary vascular resistance index (PVRI) (23. 18±6.22), right ventricular ejection fraction (RVEF) was (0. 45±0.03). right ventricular end-diastolic volume index (RVEDVI) was (51.4±6.37) in routine group, those of experimental group respectively were (31. 17±9.23) mmHg, (17.53±5.43), (0.55±0.07), (45. 17±4.71) (P〈0.05 or 〈0.01). Conclusion: The cardiac function, hemodynamics of experiment group (infusion volumed urination) is better than those of routine group after lung cancer operation,
出处 《心血管康复医学杂志》 CAS 2007年第2期172-175,共4页 Chinese Journal of Cardiovascular Rehabilitation Medicine
关键词 血浆容量 水电解质平衡 胸外科手术 心室功能 Plasma volume Water-electrolyte balance Chest surgery Ventricular function, right
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