摘要
目的:研究左氧氟沙星治疗复治涂阳肺结核患者的临床效果。方法:选取72例复治涂阳肺结核患者为研究对象,采用随机数字表法分为观察组和对照组各36例。对照组采用常规化疗方案治疗,观察组在对照组基础上采用左氧氟沙星治疗,比较两组患者的治疗效果。结果:治疗8个月后,观察组患者的阴转率为88.89%(32/36),优于对照组的77.78%(28/36),差异无统计学意义(P>0.05);观察组患者的病灶吸收率为97.22%(35/36),高于对照组的80.56%(29/36),差异有统计学意义(P<0.05);观察组的临床总有效率为100.00%(36/36),高于对照组的80.56%(29/36),差异有统计学意义(P<0.05);观察组不良反应发生率为11.11%(4/36),与对照组的19.44%(7/36)比较,差异无统计学意义(P>0.05)。结论:在常规化疗方案基础上采用左氧氟沙星治疗复治涂阳肺结核患者的临床效果优于常规化疗方案治疗效果。
Objective:To study clinical effects of Levofloxacin on retreatment of smear-positive pulmonary tuberculosis.Methods:72patients with smear-positive pulmonary tuberculosis were selected as the study subjects,and they were divided into observation group and control group by the random number table method,36cases in each.The control group was treated with conventional chemotherapy,while the observation group was treated with Levofloxacin on the basis of that of the control group.The therapeutic effects of the two groups were compared.Results:8months after the treatment,the negative conversion rate of the observation group was88.89%(32/36),which was better than that of the control group(77.78%,28/36),and the difference was not statistically significant(P>0.05).The lesion absorption rate of the observation group was97.22%(35/36),which was higher than that of the control group(80.56%,29/36),and the difference was statistically significant(P<0.05).The total clinical effective rate of the observation group was100.00%(36/36),which was higher than that of the control group(80.56%,29/36),and the difference was statistically significant(P<0.05).Further,the incidences of adverse reactions in the observation group and the control group were11.11%(4/36)and19.44%(7/36),respectively,and the difference was not statistically significant(P>0.05).Conclusions:Based on the conventional chemotherapy protocol,Levofloxacin is superior to the conventional chemotherapy protocol on the retreatment of smear-positive pulmonary tuberculosis.
作者
赵德生
ZHAO Desheng(Benxi Infectious Disease Hospital, Benxi Liaoning 117000, China))
出处
《中国民康医学》
2018年第23期6-7,33,共3页
Medical Journal of Chinese People’s Health
关键词
左氧氟沙星
复治涂阳肺结核
化疗
Levofloxacin
Retreatment of smear-positive pulmonary tuberculosis
chemotherapy
