摘要
目的探讨难产产妇应用哌替啶干预的临床效果及对产程时间的影响。方法选取2016年1月——2017年1月住院分娩的难产产妇90例作为研究对象。根据是否对产妇进行药物干预分为对照组和研究组,每组45例,对照组不给予任何药物干预,研究组给予哌替啶干预。观察哌替啶干预对宫缩频率和强度的影响,对比两组产程时间变化以及分娩率差异,对比两组新生儿Apgar评分和新生儿行为神经测定(NBNA)评分,记录两组并发症和药物不良反应的发生情况。结果干预后60 min,研究组宫缩频率快于干预前,宫缩强度强于干预前(P <0. 05)。研究组的第一、第二、第三产程时间及总产程时间均短于对照组,分娩率和不良反应总发生率高于对照组,并发症总发生率低于对照组(P <0. 05)。研究组新生儿出生5 min的Apgar评分低于对照组,出生7 d的NBNA评分高于对照组(P <0. 05)。结论哌替啶干预难产产妇分娩,可缩短产程,加快宫缩频率,增强宫缩强度,改善新生儿状况,减少并发症。
Objective To investigate clinical effectiveness of Pethidine in intervention of dystocia women and its effect on labor time.Methods A total of 90 dystocia women admitted during January 2016 and January 2017 were selected in the study,and the women were divided into control group and study group(n=45 for each group)according to whether or not having maternal drug intervention.Control group did not give any drug intervention,while study group was given Pethidine intervention.In two groups,effects of Pethidine intervention on frequency and intensity of uterine contraction were observed;changes of labor duration and delivery rate were compared;Apgar score and neonatal behavioral neurological assessment(NBNA)score were compared;incidence rates of complications and drug adverse reactions were recorded.Results After intervention for 60 minutes,uterine contraction frequency was faster,and uterine contraction intensity was stronger than those before intervention in study group(P<0.05).In study group,the first,second and third stages of labor and the total stages of labor were significantly shorter,while delivery rate and the total incidence rate of adverse reactions were significantly higher,and the total incidence rate of complications was significantly lower than those in control group(P<0.05).In study group,Apgar score on 5 min after giving birth was significantly lower,while NBNA score at 7 d after giving birth was significantly higher than those in control group(P<0.05).Conclusion Pethidine in intervention of delivery of dystocia women may shorten labor time,accelerate frequency of uterine contraction,enhance intensity of uterine contraction,improve condition of newborns and reduce incidence rate of complications.
作者
常丽锦
吕亚淑
马会
高娟
郭战
CHANG Li-jin;Lv Ya-shu;MA Hui;GAO Juan;GUO Zhan(Department of Gynecology&Obstetrics,the First Hospital Affiliated to Hebei North College,Zhangjiakou,Hebei 075000,China;Department of Gynecology&Obstetrics,Maternal and Child Health Hospital of Baoding,Baoding,Hebei 071066,China)
出处
《解放军医药杂志》
CAS
2018年第12期109-112,共4页
Medical & Pharmaceutical Journal of Chinese People’s Liberation Army
基金
河北省科技计划项目(162777264)
关键词
难产
哌替啶
产程
治疗效果
Dystocia
Pethidine
Obstetric labor
Treatment effectiveness
