摘要
目的:利用Meta分析探讨脐敷治疗的可行性与有效性,探讨中药脐敷治疗本病的临床意义,为中药脐敷的临床运用提供依据。方法:检索有关脐敷治疗本病的随机对照试验(RCT)的文献。运用RevMan5. 3软件进行分析。结果:共有18项RCT符合纳入研究标准,772例接受脐敷治疗,697例接受其他方法对照治疗。脐敷组的治疗有效率、腹痛改善率、大便次数改善率、大便性状改善率的RR分别明显优于对照组。安全性方面,脐敷组RR=1. 70(95%CI为0. 67,4. 32; P=0. 27),说明两组不良反应无明显差异。各观察指标的漏斗图均基本呈现左右对称的倒漏斗图形,提示无发表偏倚。结论 :脐敷治疗腹泻型肠易激综合征具有较好的可行性、有效性与安全性,值得今后临床上深入研究推广应用。
Objective:To analyze the effectiveness and feasibility of navel application treating diarrhea-predominant irritable bowel syndrome(IBS-D),so as to provide an objective evidence for its clinical treatment.Methods:RCTs studies on navel application treating IBS-D were retrieved and analyzed with RevMan5.3software.Results:There were a total of18RCTs met the inclusion criteria,among which,772cases were treated with navel application,and697cases were treated with other therapies.The RR value of total treatment effective rates,abdominal pain improvement rates,defecate frequency improvement rates,stool property improvement rates in the navel application group were respectively superior to those in the control group.In terms of safety,P value of the navel application group was0.27;which showed that there was no difference in adverse reactions between the two groups.The funnel plots of each inspection index presented symmetrical graphics,which indicated that there were no publication bias.Conclusion:Navel application is effective,feasible and safe in treatment of IBS-D,which is worth widely applied in clinic.
作者
钱赟达
黄宣
郑红斌
QIAN Yunda;HUANG Xuan;ZHENG Hongbin(Jiaxing TCM Hospital Affiliated to Zhejiang Chinese Medical University, Jiaxing 314001, China;The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China;Basic Medical College of Zhejiang University of Traditional Chinese Medicine,Hangzhou 310053, China)
出处
《中医药学报》
CAS
2018年第6期102-105,共4页
Acta Chinese Medicine and Pharmacology
