摘要
背景:三维外固定支架材质及构架经过有效的改良后能获得良好的治疗效果,再加上该固定方法具有微创性,有望成为老年骨质疏松骨折的有效固定方法,但是对于其固定应用后生物力学稳定性研究较少。目的:探讨三维外固定支架在老年骨质疏松骨折患者中的应用效果及生物力学稳定性,为老年骨质疏松骨折提供治疗依据。方法:2017年6月至2018年6月选择老年尸体胫骨标本36根作为实验对象,经18%EDTA脱钙法建立胫骨标本骨质疏松模型后制备胫骨中段短斜型骨折模型,并随机分为3组(n=12),分别给予钢板(钢板组)、髓内钉(髓内钉组)、三维外固定支架(三维外固定支架组)进行骨折固定。每组随机取4根标本放置在BOSE3300生物力学实验机上完成抗压缩力学、抗弯曲力学及抗扭转力学测定,比较不同固定方法的生物力学性能。结果与结论:(1)轴向力测定:三维外固定支架组在250,500N轴向力作用下位移量大于髓内钉组,小于钢板组(P均<0.05);而在750 N轴向力作用下位移量小于其他2组(P <0.05);(2)抗弯曲力测定:不同弯曲力作用下三维外固定支架组挠度均小于钢板组和髓内钉组(P<0.05),髓内钉组挠度均小于钢板组(P<0.05);(3)抗扭转力学测定:不同扭转力作用下,三维外固定支架组扭转角均小于髓内钉组和钢板组(P<0.05),髓内钉组扭转角均小于钢板组(P <0.05);(4)结果提示,三维外固定支架用于老年骨质疏松骨折中能获得良好的生物力学稳定性,从生物力学角度可将其推广应用。
BACKGROUND:Improved three-dimensional external fixator can obtain good treatment effect and is expected to become a new effective fixation method for osteoporotic fracture in the elderly for minimally invasion.However,little is reported on its mechanical stability after fixation.OBJECTIVE:To investigate the biomechanical effect of three-dimensional external fixator for aged patients with osteoporotic fractures and provide evidence for its clinical application.METHODS:From June 2017 to June 2018,36 aged tibial specimens were selected to prepare the tibia osteoporosis specimen models by 18%EDTA decalcification.After successful modeling,the short oblique osteoporosis fracture model of the middle tibia was established.Then these tibial specimens were randomly divided into three groups(n=12 per group),and fixed with steel plate,intramedullary nail,and three-dimensional external fixator,respectively.Four specimens randomly from each group were measured by compression test,bending test,and torsion test with the BOSE3300 biomechanical testing machine,and the differences in biomechanical stability among groups were determined.RESULTS AND CONCLUSION:(1)Under 250 and 500 N of axial force,the displacement value in the three-dimensional external fixator group was significantly higher than that in the intramedullary nail group,and lower than that in the plate group(both P<0.05).The displacement value under 750 N of axial force in the three-dimensional external fixator group was significantly lower than that in the other two groups(P<0.05).(2)In the bending test,the deflection under different bending forces in the three-dimensional external fixator group was smaller than that in the other two groups(P<0.05).The deflection in the intramedullary nail group was smaller than that in the plate group(P<0.05).(3)The torsional angle in the three-dimensional external fixator group was smaller than that in the other two groups under different torsion forces(P<0.05).The torsional angle in the intramedullary nail group was smaller than tha
作者
刘瑶
黄跃
刘勇
罗玉茹
罗婧
鞠梅
Liu Yao;Huang Yue;Liu Yong;Luo Yuru;Luo Jing;Ju Mei(School of Nursing, Southwest Medical
University, Luzhou 646000, Sichuan Province, China; Stomatology Hospital Affiliated to Southwest Medical
University, Luzhou 646000, Sichuan Province, China; Department of Traumatic Orthopedics, Chinese
Medicine Hospital Affiliated to Southwest Medical University, Luzhou 646000, Sichuan Province, China)
出处
《中国组织工程研究》
CAS
北大核心
2018年第35期5602-5606,共5页
Chinese Journal of Tissue Engineering Research
基金
国家自然科学基金青年项目(81300903)
国家社会科学基金项目(16XSH017)
四川省大学生创新创业训练计划项目(201710632096)。
