摘要
目的:探讨妊娠期糖尿病(gestational diabetes mellitus,GDM)孕妇产后血糖水平并分析影响糖代谢异常的相关因素。方法:回顾性分析孝感市中心医院2015年1月～2017年1月收治的妊娠期糖尿病患者200例,根据产后8周时血糖恢复情况分为A组(血糖正常组)和B组(血糖异常组),将可能影响产后血糖转归的因素包括年龄、民族、吸烟史、糖尿病家族史、孕前BMI、产前BMI、产后锻炼时间等进行单因素分析,然后将单因素分析有统计学意义的指标进行非条件二分类Logistic多因素回归分析。结果:143例(71. 5%)患者产后8周血糖恢复正常,57例(28. 5%)患者糖代谢异常(糖尿病6例,空腹血糖受损11例,糖耐量受损40例)。单因素分析显示糖尿病家族史、年龄、孕前BMI、产前BMI以及产后锻炼时间和产后糖代谢异常有关,多因素分析显示糖尿病家族史、孕前BMI是产后糖代谢异常的独立危险因素。结论:GDM患者产后糖代谢异常发生率较高,糖尿病家族史、孕前BMI和产后糖代谢异常密切相关,应加强产后运动锻炼。
Objective:To investigate the situation of postpartum blood glucose abnormalities in pregnant women with gestational diabetes mellitus(GDM)and analyze the possible influencing factors of these patients.Methods:200 pregnant women with GDM from Jan.2015 to Jan.2017 in Xiaogan Central Hospital in Hubei Province were selected randomly by retrospective study.According to their postpartum blood glucose in the eighth week,these patients were divided into group A(with normal blood glucose)and group B(with abnormal blood glucose).The possible influencing factors included age,nation,smoking habit,diabetes mellitus(DM)family history,pre-pregnancy body mass index(BMI),prenatal BMI and postpartum physical exercise time and thus one-way ANOVA analysis was made.Then Logistic regression analysis was made on the basis of the indexes with statistical significance from the results of one-way ANOVA analysis.Results:143(71.5)women's postpartum blood glucose was normal in the eighth week,while 57(28.5%)patients were abnormal,including 6 with DM,11 with impaired fasting glucose(IFG)and 40 with impaired glucose tolerance(IGT).Univariate analysis showed that DM family history,age,pre-pregnancy BMI,prenatal BMI,postpartum exercise time were associated with abnormal postpartum blood glucose.Multifactor regression analysis indicated that DM family history and pre-pregnancy BMI were the independent influencing factors for postpartum blood glucose abnormalities in pregnant women with GDM.Conclusion:The occurrence of abnormal postpartum blood glucose in pregnant women with GDM proves to be high and there is close relationship between abnormal postpartum blood glucose and DM family history as well as pre-pregnancy BMI.In addition,it is a must to strengthen postpartum physical exercise for postpartum women with GDM.
作者
叶芬
张慧莉
YE Fen;ZHANG Hui-li(School of Medicine,Hubei Polytechnic Institute,Xiaogan,Hubei 450002,China;;Xiaogan Central Hospital,Xiaogan,Hubei 432000,China)
出处
《湖北职业技术学院学报》
2018年第3期110-112,35,共4页
Journal of Hubei Polytechnic Institute
