摘要
星状神经节(stellate ganglion,SG)在功能上属于交感神经节,星状神经节阻滞(stellate ganglion block,SGB)是指通过各种方法使星状神经节所支配区域——头、面、颈、上肢及上胸部交感神经阻滞的方法,且已证实其在全身多个系统产生治疗或保护作用,但具体机制尚未阐明;大鼠SG的解剖和功能与人类类似,是模仿人类SGB的理想模型,大鼠SGB模型的建立将为研究SGB的分子生物学种种机制提供基础。当前对大鼠星状神经节阻滞的方法鲜有描述,大多作为实验操作部分简单带过,尚未有文献对其进行相关总结,故在此就大鼠SGB模型建立方法进行综述。
The stellate ganglion(SG)is functionally a sympathetic ganglion.Stellate ganglion block(SGB)refers to a variety of methods for sympathetic blockade of the head,face,neck,upper limbs,and upper chest,which are innervated by stellate ganglia.SGB has been demonstrated to produce therapeutic or protective effects in multiple systems throughout the body,but the exact mechanism involved has not yet been elucidated.Rat SG resembles the anatomy and function of the equivalent system in human,so rat is an ideal model for mimicking human SGB and can provide a basis for researching the molecular biological mechanism behind the effects of SGB.At present,the methods of rat SGB have rarely been described and mostly have been simply mentioned as part of the experimental operation,and there is no literature to summarize the approaches used.Therefore,the method for establishing the rat SGB model is reviewed here.
作者
胡可
张炳东
HU Ke;ZHANG Bingdong(First Affiliated Hospital of Guangxi Medical University,Nanning 530000,China)
出处
《中国比较医学杂志》
CAS
北大核心
2018年第9期115-119,共5页
Chinese Journal of Comparative Medicine
基金
广西重点研发计划(桂科AB16380240)
关键词
星状神经节
交感神经系统
神经阻滞
大鼠
stellate ganglion
sympathetic nervous system
nerve block
rat
