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中青年阻塞性睡眠呼吸暂停综合征与缺血性脑卒中关系的临床研究

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摘要 目的:对中青年阻塞性睡眠呼吸暂停综合征与缺血性脑卒中的相关性进行探讨。方法:选取我院2016年9月至2017年9月我院收治的缺血性脑卒中合并阻塞性睡眠呼吸暂停综合征患者76例作为观察组,同期选取单纯缺血性脑卒中患者76例作为对照组,对两组相关指标进行对比。结果:在HCY(同型半胱氨酸)、hs-CRP(超敏C反应蛋白)、Fg(纤维蛋白原)及颈动脉IMT(颈动脉内-中膜厚度)指标对比中,观察组各指标均明显高于对照组,差异有统计学意义,P<0.05;斑块发生率方面,观察组(93.42%)明显高于对照组(53.95%),差异有统计学意义,P<0.05。结论:对于中青年阻塞性睡眠呼吸暂停综合征患者而言,凝血异常、高HCY血症、炎症反应及动脉粥样硬化,都可能导致缺血性脑卒中的发生。 Objective:To investigate the relationship between obstructive sleep apnea syndrome and ischemic stroke in young and middle-aged.Methods:with ischemic stroke in our hospital from September 2016 to September 2017 in our hospital with obstructive sleep apnea syndrome patients 76 cases as the observation group,selected patients with ischemic stroke in 76 cases as control group,compared two groups of related index.Results:in HCY(homocysteine(hs-CRP),high sensitive C reactive protein(Fg),fibrinogen(IMT)and carotid artery intima-media thickness)index contrast,observation group were significantly higher than the control group,the difference was statistically significant,P<0.05;plaque.Rate,the observation group(93.42%)was significantly higher than the control group(53.95%),the difference was statistically significant,P<0.05.Conclusion:for young and middle-aged patients with obstructive sleep apnea syndrome,coagulation disorders,hyperHCY,inflammation and atherosclerosis may lead to the occurrence of ischemic stroke.
出处 《湖南中医药大学学报》 CAS 2018年第A01期928-929,共2页 Journal of Hunan University of Chinese Medicine
关键词 缺血性脑卒中 阻塞性睡眠呼吸暂停综合征 中青年 相关性 Ischemic stroke Obstructive sleep apnea syndrome Middle and young people Correlation
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