摘要
目的:分析奥美拉唑三联疗法与雷尼替丁三联疗法治疗小儿消化性溃疡的临床疗效。方法:选取2016年9月-2017年9月笔者所在医院收治的经内窥镜确诊为消化性溃疡患儿71例,根据治疗方法不同分为两组,对照组34例应用雷尼替丁三联疗法治疗,研究组37例应用奥美拉唑三联疗法治疗,比较两组治疗效果、不良反应及幽门螺旋杆菌(Hp)清除率。结果:对照组治疗总有效率为82.35%,低于研究组的97.3%,不良反应发生率为11.76%,高于研究组的8.11%,Hp根除率为76.47%,低于研究组的94.59%,比较差异均有统计学意义(P<0.05)。结论:奥美拉唑三联疗法治疗患儿消化性溃疡整体治疗效果更佳。
Objective:To analyze the clinical efficacy of Omeprazole triple therapy and Ranitidine triple therapy in the treatment of pediatric peptic ulcer.Method:From December 2016 to December 2017,71 cases of peptic ulcer diagnosed by endoscopy in the author’s hospital were selected and divided into two groups according to different treatment methods.In the control group,34 patients were treated with Ranitidine triple therapy,and 37 patients in the study group were treated with Omeprazole triple therapy.The treatment effects,adverse reactions,and helicobacter pylori(Hp)eradication rate were compared between the two groups.Result:The total effective rate of the control group was 82.35%,which was lower than the 97.3%of the study group,the incidence of adverse reactions was 11.76%,which was higher than the 8.11%of the study group,the Hp eradication rate was 76.47%,which was lower than the study group’s 94.59%,and the differences were statistically significant(P<0.05).Conclusion:Omeprazole triple therapy is better for overall treatment effect of pediatric peptic ulcer.
作者
李翊雯
张军利
咸哲民
LI Yiwen;ZHANG Junli;XIAN Zhemin(Yanbian University,Yanji 133000,China)
出处
《中外医学研究》
2018年第19期19-20,共2页
CHINESE AND FOREIGN MEDICAL RESEARCH
