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孟鲁司特钠联合酮替芬治疗小儿支气管炎的临床效果分析 被引量:4

Clinical Analysis of Montelukast Sodium Combined With Ketotifen in the Treatment of Bronchitis in Children
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摘要 目的分析孟鲁司特钠联合酮替芬治疗小儿支气管炎的临床疗效。方法随机选取我院2014年10月~2017年2月收治的200例支气管炎患儿,随机分为观察组和对照组各100例。对照组给予静脉使用抗生素加口服丙卡特罗和氨溴索雾化吸入治疗,观察组在对照组基础上给予口服孟鲁司特钠联合酮替芬治疗,比较两组患儿临床治疗效果和恢复情况。结果在治疗的总有效率上比较,观察组比对照组明显更高(P<0.05);在咳嗽消失时间及肺部喘鸣音消失时间上比较,观察组比对照组明显更短(P<0.05);两组在不良反应发生率上比较无明显差异(P>0.05)。结论孟鲁司特钠联合酮替芬治疗小儿支气管炎效果确切,能有效改善患儿临床症状,促进患儿恢复,且安全性高,值得推广使用。 Objective To analyze the clinical efficacy of Montelukast combined with ketotifen treatment of infantile bronchitis.Methods 200 cases of bronchitis patients in our hospital in October 2014 to February 2017 were randomly selected,randomly divided into observation group and control group with 100 cases in each group.The control group was given intravenous antibiotics plus oral Bin Castro and ambroxol inhalation therapy,the observation group was given oral montelukast sodium combined with ketotifen on the basis of the control group,and the clinical effects and recovery of the two groups were compared.Results In the treatment of the total efficiency comparison,the observation group was significantly higher than the control group(P<0.05);compare the disappearance time of cough and pulmonary wheezing disappearance time,the observation group than in control group was significantly shorter(P<0.05);the two groups in the incidence of adverse reactions compared with no significant difference(P>0.05).Conclusion Montelukast Combined with ketotifen treatment of infantile bronchitis effect,can effectively improve the clinical symptoms,promote their recovery,and high safety,and is worthy of promotion.
作者 李波 LI Bo(Department of Pharmacy,Zhongxiang People's Hospital,Zhongxiang 431900,Hubei,China)
出处 《医学信息》 2018年第2期130-132,共3页 Journal of Medical Information
关键词 小儿支气管炎 孟鲁司特钠 酮替芬 Infantile bronchitis Montelukast sodium Ketotifen
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