摘要
目的:探讨益肺宣降汤加减联合喘可治穴位注射对支气管哮喘急性发作期肺功能及生活质量的影响。方法:选取2015年3月-2017年3月江门市第二人民医院支气管哮喘急性发作期患者96例,依据抽签法分组,各48例。对照组仅采取常规治疗,观察组于此基础上联合益肺宣降汤加减+喘可治穴位注射治疗,两组均治疗4周。对比两组入院时、治疗4周后肺功能各指标[呼气峰流量(PEF)、第1秒呼气量(FEV_1)、FEV_1/用力肺活量(FVC)]水平及不良反应发生率,治疗后随访2个月比较两组入院时、治疗后2个月生活质量评分(SF-36)。结果:入院时两组PEF、FEV_1、FEV_1/FVC比较,差异无统计学意义(P>0.05),治疗4周后与对照组相比,观察组PEF、FEV_1、FEV_1/FVC均提高,差异有统计学意义(P<0.05);入院时两组SF-36评分相比,差异无统计学意义(P>0.05),治疗后2个月两组SF-36评分均提高,且观察组高于对照组,差异有统计学意义(P<0.05);观察组不良反应发生率为12.50%(6/48),与对照组的8.34%(4/48)相比,差异无统计学意义(P>0.05)。结论:予以支气管哮喘急性发作期患者益肺宣降汤加减联合喘可治穴位注射治疗可明显改善肺功能,提高其生活质量,且安全性较高。
Objective:To explore clinical efficacy of the Yifei Xuanjiang decoction(益肺宣降汤)plus the Chuankezhi injection(喘可治注射液)on pulmonary function with the quality of life in patients with bronchial asthma at acute stage.Methods:96 patients were grouped according to the lottery method,48 cases in each.The control group only take conventional treatment;the observation group received the Yifei Xuanjiang decoction plus the Chuankezhi injection more,for 4 weeks.Results:There was no significant difference in PEF,FEV1 and FEV1/FVC between two groups at admission(P>0.05).After 4 weeks,PEF,FEV1 and FEV1/FVC in the observation group were significantly higher than those in the control group(P<0.05).There was no significant difference in SF-36 score between two groups on admission(P>0.05).SF-36 scores in two groups were increased at 2 months after treatment,and those in the observation group was higher(P<0.05).The incidence of adverse reactions was 12.50%in the observation group and 8.34%in the control group,without a significantly difference(P>0.05).Conclusion:The Yifei Xuanjiang decoction plus the Chuankezhi injection was effective by significantly improving lung function and the quality of life,with high safety.
出处
《中医临床研究》
2018年第7期18-20,共3页
Clinical Journal Of Chinese Medicine
关键词
支气管哮喘急性发作期
益肺宣降汤
喘可治
穴位注射
肺功能
Bronchial asthma at acute stage
The Yifei Xuanjiang decoction
Chuankezhi
Point injection
Pulmonary function