摘要
本文结合国内外文献综述了油茶化学成分的研究进展,并对该植物的抗肿瘤活性进行了总结。油茶所含化学成分主要为三萜及三萜皂苷类、黄酮类、脂肪酸类、甾体类、木脂素类等。三萜及三萜皂苷类成分为油茶中最主要的化学成分。油茶提取物及单体化合物Oleiferasaponin B1、B2、C1、C2、油茶皂苷B对肿瘤细胞有抑制活性,多糖和油茶皂苷A、B具有抑制移植瘤活性,其作用机制有待进一步深入研究。
In this paper,we reviewed the research progress of the chemical constituents of Camellia oleifera Abel.and its antitumor activity.The main chemical constituents are triterpenoids and triterpenoid saponins,flavonoids,fatty acids,steroids and lignans in Camellia oleifera Abel..The triterpenoids and triterpenoid saponins are the most abundant chemical constituents in Camellia oleifera Abel..The main inhibitory activities of tumor cells were oleifera saponin B1,B2,C1,C2 and camellia saponin B.Polysaccharide,camellia saponin A and B can inhibit the tumor xenograft.The anti-tumor mechanism needs to be further studied.
作者
张军锋
吴友根
胡新文
ZHANG Jun-feng;WU You-gen;HU Xin-wen(College of materials and chemical engineering,Hainan University,Haikou 570228,China)
出处
《天然产物研究与开发》
CAS
CSCD
北大核心
2018年第4期708-716,共9页
Natural Product Research and Development
基金
海南大学青年基金(hdkyxj201716)
2017年海南省重大科技计划(ZDKJ2017004)
海南省重点研发专项(ZDYF2016157
2015ZY24)
关键词
油茶
化学成分
抗肿瘤
Camellia oleifera Abel.
chemical constituents
antitumor activity
