摘要
目的探讨不同镇静深度对心脏瓣膜术后谵妄发生率的影响。方法选取安徽省立医院心脏大血管外科2017年1月至2017年9月择期下行心脏瓣膜手术的患者30例,根据镇静深度分为浅镇静组和深镇静组,每组15例。记录两组患者的年龄、性别、受教育程度、术前血红蛋白含量、体外循环时间、主动脉夹闭时间、手术时间及麻醉过程中镇静药丙泊酚、咪达唑仑和舒芬太尼使用剂量等;对比两组患者在整个机械通气过程中丙泊酚剂量、意外拔除气管插管及谵妄的发生情况。结果浅镇静组患者丙泊酚剂量和术后谵妄发生率低于深镇静组,差异有统计学意义(P<0.05),两组患者其他指标差异无统计学意义(P>0.05)。结论轻度镇静可能有助于减轻心脏瓣膜术后谵妄发生的风险。
Objective To observe the influence of sedative depth on the incidence of delirium after cardiac valve surgery.Methods The study included 30 consecutive patients who underwent cardiac valve surgery surgery from January 2017 to September 2017.The 30 patients were randomly divided into mild sedation group(n=15)and deep sedation group(n=15),according to sedative depth.The indexes of both groups were recorded as follows:age,sex,educational level,preoperative hemoglobin concentration,the time of CPB,aortic clamp closing time,operative time,propofol/midazolam/sulfentanyl dosage during anaesthesia and proportion of abnormal extubation,the propofol dosage during mechanical ventilation and the incidence of delirium.Results Compared todeep sedation group,the propofol dosage and the incidence of postoperative delirium were significantly lower(P<0.05)inmild sedation group.The other indexes were similar between the two groups(P>0.05).Conclusion The mild sedation maybe helpful to reduce the incidence of delirium after cardiac valve surgery.
作者
张琼
朱纪荣
葛建军
ZHANG Qiong;ZHU Jirong;GE Jianjun(Department of Cardiovascular Surgery,Anhui Provincial Hospital,Hefei 230001,China)
出处
《安徽医学》
2018年第3期288-290,共3页
Anhui Medical Journal
关键词
术后谵妄
心脏瓣膜手术
镇静深度
Postoperative delirium
Cardiac valve surgery
Sedative depth
