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良性前列腺增生患者临床指标与糖尿病的相关性研究 被引量:3

CORRELATION BETWEEN CLINICAL INDEXES AND DIABETES MELLITUS IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA
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摘要 目的评估良性前列腺增生(BPH)患者的临床指标与糖尿病(DM)的关系。方法回顾性分析我院2008年至2009年652例老年前列腺增生患者。患者分为前列腺增生组(A组)、前列腺增生合并糖尿病组(B组)。评估纳入因素包括空腹血糖(FBG)、2小时餐后血糖(2hPBG)、糖化血红蛋白(HbA1c)、前列腺特异性抗原(PSA)、前列腺体积、国际前列腺症状评分(IPSS)结果前列腺增生合并糖尿病组(B组)患者的前列腺体积(51.02±20.58)ml、PSA(3.57±2.12)ng/mL和IPSS(12.05±6.31)均高于前列腺增生组(A组)患者的前列腺体积(41.14±19.81)ml、PSA(1.85±1.19)ng/mL和IPSS(8.75±6.39),差异均有统计学意义(P<0.05)。结论前列腺体积、IPSS评分、PSA与糖尿病密切相关,糖尿病可能在BPH的发生发展中发挥着重要的作用。 Objective To evaluate the relationship between clinical indexes of benign prostatic hyperplasia(BPH)patients and diabetes mellitus(DM).Methods One hundred and seventeen geriatric patients(652)with BPH were retrospectively studied between 2008 and 2009.Patients were divided into two groups:BPH,and BPH with DM groups.The effects of indexes of DM,including fasting blood glucose(FBG),2-h postprandial blood glucose(2hPBG),glycosylated hemoglobin(HbA1c),and the indexes of BPH patients including prostate-specific antigen(PSA),International Prostate Symptom Score(IPSS),prostate volume(PV),and duration of lower urinary tract symptoms(LUTS)were evaluated.Results The values of PV(51.02±20.58),PSA(3.57±2.12),and IPSS(12.05±6.31)in the BPH patients with DM group were significantly higher than PV(41.14±19.81),PSA(1.85±1.19),and IPSS(8.75±6.39)in the BPH group(P<0.05).Conclusion Our study demonstrates that PV,IPSS,PSA is closely correlated with diabetes,and diabetes may play an important role in the occurrence and development of BPH.
作者 高义胜 刘杰 张鹏 冯衍飞 孙富广 张维颉 王利瑞 王健明 谭善峰 郭丰富 GAO Yi-sheng;LIU Jie;ZHANG Peng(Linyi City People's Hospital,Linyi 276003,China;Shandong Medical College,Linyi 276000,China)
出处 《山东医学高等专科学校学报》 2018年第1期17-20,共4页 Journal of Shandong Medical College
基金 山东省医药卫生科技发展计划(2015WSA13068)
关键词 糖尿病(DM) 良性前列腺增生(BPH) 前列腺体积(PV) Diabetes mellitus(DM) Benign prostate hyperplasia(BPH) Prostate volume(PV)
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