摘要
目的探讨动态血糖监测指导个体化营养与运动联合治疗妊娠期糖尿病的效果,为妊娠期糖尿病的疗效提供评价系统。方法选取我院收治的96例妊娠期糖尿病孕妇,根据随机数字表法将孕妇平均分为观察组和对照组,每组48例。对照组孕妇给予常规妊娠糖尿病营养指导和适量运动,观察组孕妇根据血糖水平给予个体化营养与运动的联合治疗,比较2组孕妇治疗前、后血糖和血脂水平,并观察孕妇和新生儿出生体质量和妊娠结局。结果治疗前2组妊娠期糖尿病孕妇生化指标、空腹血糖(FBG)、餐后2 h血糖(2 h PBG)、糖化血红蛋白(HbA1C)、三酰甘油(TG)和总胆固醇(TC)比较差异无统计学差异(P>0.05)。经联合治疗后观察组妊娠期糖尿病孕妇生化指标(FBG、2 hPBG、HbA1C、TG和TC)显著低于治疗后对照组,差异存在统计学意义(P<0.05)。联合治疗后观察组妊娠期糖尿病孕妇孕期总增重、每周增重、孕期体质量指数(BMI)增加和每周BMI增加以及新生儿出生体质量均明显低于治疗后对照组,同时观察组孕妇子痫前期、早产、羊水过多、巨大儿、剖宫产和产后出血比例均明显低于对照组,差异存在统计学意义(P<0.05)。结论动态血糖监测指导的个体化营养与运动的联合治疗能够降低妊娠期糖尿病孕妇血糖、血脂水平,改善孕妇和胎儿体质量,降低不良妊娠结局的产生,为妊娠糖尿病的综合治疗提供参考。
To investigate the effects of individualized nutrition support guided by continuous blood glucose monitoring combined with exercise therapy on gestational diabetes mellitus,so as to provide a possible evaluation system for gestational diabetes mellitus treatment.A total of 96 pregnant women with diabetes mellitus admitted into the hospital were enrolled for the study and were randomly divided into the observation group and the control group,each consisting of 48 subjects.The pregnant women in the control group received routine nutritional guidance and had proper exercise as instructed,while those in the observation group had individualized nutrition support combined with proper exercise,in accordance with the level of blood sugar.Then,blood glucose and blood lipid levels before and after treatment were detected and compared between the subjects of the 2 groups,and infant body weight and pregnancy outcome were closely observed and recorded.Before treatment,there were no statistical differences in the levels of fasting blood glucose(FBG),blood glucose 2 hour after meal,glycosylated hemoglobin(HbA1C),glycerin trilaurate(TG)and total cholesterol(TC),when comparisons were made between the 2 groups(P>0.05).After treatment,the levels of the biochemical indexes mentioned above in the observation group were significantly lower than those of the control group,and statistical significance could be noted when comparisons were made between the 2 groups(P<0.05).After treatment,rates of total weight gain during pregnancy,weekly gain weight,BMI increase during pregnancy,BMI increased per week and weekly BMI and neonatal weight of the observation group were significantly lower than those of the control group(P<0.05).At the same time,after treatment,rates of preeclampsia,premature birth,excess amniotic fluid,huge infant,cesarean section and postpartum hemorrhage in the observation group,were all significantly lower than those in the control group,with statistical significance(P<0.05).Individualized nutrition support guided by cont
作者
胡玉菊
李淑娟
胡可佳
杨学军
Hu Yuju;Li Shujuan;Hu Kejia;Yang Xuejun(Department of Gynaecology and Obstetrics,Shunyi Hospital,Beijing 101300,China)
出处
《海军医学杂志》
2018年第1期58-61,65,共5页
Journal of Navy Medicine
基金
北京市顺义区科技计划项目(201404)
关键词
妊娠糖尿病
动态血糖监测
个体化营养
联合治疗
运动
Gestational diabetes
Continuous blood glucose monitoring
Individualized nutrition
Combined treatment
Exercise
