摘要
目的:对贝那普利联合缬沙坦应用于糖尿病肾病临床治疗中的效果进行观察。方法:选取98例2014年3月~2017年1月期间在某院接受治疗的糖尿病肾病患者,并1∶1随机分为参照组和实验组各49例,对分别应用单纯贝那普利和贝那普利联合缬沙坦治疗的效果进行对照研究。结果:就尿微量白蛋白、24h尿蛋白定量、空腹血糖以及餐后2h血糖水平等指标而言,实验组均明显低于参照组;就治疗总有效率而言,实验组明显高于参照组;就不良反应发生率而言,实验组明显低于参照组,P<0.05,组间差异具有统计学意义。结论:贝那普利联合缬沙坦应用于糖尿病肾病临床治疗中的效果十分理想,值得大力推广。
Objective:To observe the effect of Benner Pury combined with valsartan in the treatment of diabetic nephropathy.Methods:98 cases of patients with diabetic nephropathy treated in a hospital from March 2014 to January 2017 were selected and randomly divided into control group and experimental group,with 49 patients in each group.The two groups were treated with simple Benner Pury and Benner Pury combined with valsartan,respectively,then the treatment effect of the two groups were compared.Results:In terms of 24 h urinary protein quantification,fasting blood glucose and postprandial 2 h glucose level,the experimental group was significantly lower than the control group.In terms of the total effective rate of treatment,the experimental group was significantly higher than the control group.As far as the incidence of adverse reactions was concerned,the experimental group was significantly lower than the control group(P<0.05),there was significant difference between the two groups.Conclusion:Benner Pury combined with valsartan in the treatment of diabetic nephropathy has very ideal effect,which is worth popularizing.
作者
李景萍
Li Jingping(Dongfang Hospital,Luoyang,Luoyang 471003)
出处
《数理医药学杂志》
2018年第4期563-564,共2页
Journal of Mathematical Medicine
关键词
贝那普利
缬沙坦
糖尿病肾病
Benner Pury
valsartan
diabetic nephropathy