摘要
目的探讨地佐辛注射液缓解术后疼痛的临床效果和安全性。方法将于本院行外科手术的患者158例随机分为对照组和治疗组,各79例。两组患者术后均采取自控静脉镇痛,对照组给予舒芬太尼,治疗组采取地佐辛注射液。比较两组术后各时间点镇痛及镇静效果和不良反应发生率。结果从术后6 h开始,治疗组患者的NRS及Ramsay评分低于对照组(P<0.05)。治疗组嗜睡、尿潴留、瘙痒、呼吸抑制发生率均低于对照组(P<0.05)。结论地佐辛注射液可有效缓解术后疼痛,且镇静效果良好,用药安全性高,值得临床推广。
Objective To investigate the efficacy and safety of the dezocine injection in relieving postoperative pain.Methods A total o f 158 patients undergoing surgery in our hospital were selected and randomly divided into control group and treatment group by simple randomized method,with 79 cases in each group.Patients of both groups received self-controlled intravenous analgesia.The control group received sufentanil,the treatment group received dezocine injection.The analgesic,sedation effects at each postoperative time points and the incidence of adverse reactions were compared between the two groups.Results From 6 h after operation,the scores of NRS and Ramsay in the treatment group were lower than those in the control group(P<0.05).The incidence rate of lethargy,urinary retention,ltching and respiratory depression in the treatment group were lower than those in the control group(P<0.05).Conclusion Dezocine injection can effectively relieve postoperative pain,and the sedation effect is good,with high drug safety,which is worthy of clinical promotion.
作者
王平
霍彦龙
WANG Ping;HUO Yon-long(Pharmacy Department the People's Hospital ofWuqi County,Yan'an 717600,China;Anesthesiology Department,the People's Hospital ofWuqi County,Yan'an 717600,China)
出处
《临床医学研究与实践》
2018年第9期95-96,共2页
Clinical Research and Practice
