摘要
目的：探讨应用地佐辛注射液静脉注射进行术后自控镇痛的临床效果。方法：将180例肛肠外科老年患者作为研究对象,按照随机数字表法分为观察组和对照组各90例,对照组患者应用芬太尼注射液,观察组患者应用地佐辛注射液,观察2组患者2、6、12、24、48 h的视觉模拟评分（visualanaloguescale,VAS）、Ramsay评分,比较2组患者的不良反应发生情况。结果：2组患者各时间段VAS评分均在2分以下,且呈逐渐降低趋势;Ramsay评分均在2-3分范围内,2组的差异无统计学意义（P〉0.05）;观察组患者的不良反应率为7.78%（7/90）,显著低于对照组的18.89%（17/90）,2组的差异有统计学意义（P〈0.05）。结论：患者术后自控镇痛应用地佐辛注射液效果确切,安全性高,值得临床推广。
OBJECTIVE： To probe into the clinical efficacy of dezocine intravenous fluid in treatment of postoperative patient-controlled analgesia. METHODS： 180 cases of elderly patients in anal-colorectal surgery were selected to be divided into observation group and control group via random number table,with 90 cases in each group.The control group received fentanyl injection, and the observation group received dezocine injection; the visualanaloguescale（ VAS） scores,Ramsay scores of 2 h,6 h,12 h,24 h,48 h in two group of patients were observed,and the adverse reactions of two group of patients were compared. RESULTS： The VAS scores in two groups with different time points were below 2,and showed a decreasing trend with time; the Ramsay scores were at the range of2-3,there were no statistically significant difference between two groups（ P〉0. 05）. The rate of adverse reactions in observation group were [7. 78%（ 7 /90） ],significantly lower than that in control group[18. 89%（ 17 /90） ],with statistically significant difference（ P〈0. 05）. CONCLUSIONS： Dezocine intravenous fluid in treatment of postoperative patient-controlled analgesia has a good clinical efficacy and high security,which is worthy of clinical promotion.
出处
《中国医院用药评价与分析》
2015年第10期1302-1303,共2页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
地佐辛注射液
芬太尼注射液
自控镇痛
Dezocine intravenous fluid
Fentanyl injection
Patient-controlled analgesia
