摘要
目的:观察河车虫草胶囊联合八段锦治疗慢性阻塞性肺疾病(COPD)稳定期的疗效。方法:使用随机平行对照方法,将87例门诊COPD稳定期患者按病案号抽签方法简单随机分为2组。对照组43例常规治疗;治疗组44例除常规治疗外口服河车虫草胶囊,每次4粒,3次/d,并联合八段锦康复锻炼。观察2组患者治疗前及治疗后6个月6分钟步行距离、COPD评估测试(CAT)评分、肺通气功能和诱导痰中肿瘤坏死因子α(TNF-α)、白细胞介素8(I L-8)水平。结果:治疗组治疗前后6分钟步行距离、CAT评分、肺功能状况均有改善(P<0.05),诱导痰中TNF-α、I L-8水平较治疗前明显下降(P<0.05);与对照组比较,各项指标差异均有统计学意义(P<0.05)。结论:河车虫草胶囊联合八段锦锻炼能减轻气道炎症,提高患者生活质量,延缓肺功能进行性下降。
Objective:To observe clinical effects of HeChe(placenta hominis)ChongCao(cordyceps)capsules combined with eigh-section brocade in treating chronic obstructive pulmonary disease(COPD)at stationary phase.Methods:By using randomized parallel control method,87COPD patients were randomized into two groups according to the patient's ID number.Forty-three cases in the control group accepted conventional therapy,and Forty-four cases in the treatment group took HeChe ChongCao capsules besides conventional therapy,four pills each time,three times each day,they accepted eigh-section brocade to perform rehabilitation exercise.The levels of TNF-αand IL-8in the induced sputum,pulmonary ventilation function,COPD CAT scales and six-minute walking distance in both groups were observed before and after treating.Results:Six-minute walking distance,CAT scales and pulmonary functions in the treatment group were improved(P<0.05),the levels of TNF-αand IL-8in the induced sputum were lowered compared with before treating notably(P<0.05);compared with the control group,the differences had statistical meaning in different indexes(P<0.05).Conclusion:HeChe ChongCao capsules combined with eigh-section brocade could relieve airway inflammation,improve quality of life and delay progressive decline of pulmonary function.
作者
主父瑶
ZHU Fuyao(The Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210017, China)
出处
《西部中医药》
2018年第3期89-91,共3页
Western Journal of Traditional Chinese Medicine
