摘要
目的优选徐长卿超临界二氧化碳(CO_2)提取工艺条件。方法以丹皮酚提取量为考察指标,采用高效液相色谱法测定其丹皮酚的含量,采用星点设计-效应面法优选其提取条件。结果优选工艺条件为萃取压力10.81 MPa,萃取温度为55℃,CO_2流量为59.91 L·h^(-1),萃取时间为2.42 h。结论优选工艺萃取徐长卿中丹皮酚含量较高,工艺稳定可行。
ObjectiveTo optimize the supercritical CO2extraction technology condition of radix cynanchi paniculati.MethodsThe paeonol extract was used as indexes.The content of paeonol was determined by high performance liquid chromatography method.The extraction condition was optimize tby design-response surface method.ResultsThe optimum process conditions for the extraction pressure was10.81MPa,extraction temperature was55℃,flow rate of CO2was59.91L·h-1,extraction time was2.42h.ConclusionThe content of paeonol with optimum extraction process of radix cynanchi paniculati is high,process is stable and feasible.
作者
杨全伟
程璐
张耕
胡松
YANG Quanwei;CHENG Lu;ZHANG Geng;HU Song(Department of Pharmacy,the First Hospital of Wuhan City,Wuhan 430022,China)
出处
《医药导报》
CAS
北大核心
2018年第1期85-87,共3页
Herald of Medicine
基金
武汉市卫生局课题(WZ11D06)
关键词
徐长卿
丹皮酚
星点设计效应面法
萃取
二氧化碳
超临界
色谱法
高效液相
Paniculate swallowwort
Paeonal
Design-response surface method
Extraction,CO2, supercritical
Chromatography ,high performance liquid
