摘要
目的:研究香砂六君子汤加减对功能性消化不良患者胃肠动力及胃肠激素的影响。方法:选取60例功能性消化不良患者为病例组,随机分为治疗组(30例)和对照组(30例),治疗组给予口服香砂六君子加减方(党参20g,白术15g,茯苓15g,炙甘草10g,木香10g,砂仁10g,柴胡12g,香附15g,厚朴15g,枳实15g,半夏10g,陈皮10g,白芍10g,丹参15g);对照组30例,给予莫沙必利5mg,口服,3次/d,疗程设定为4周,服用前以及服用后4周分别进行胃排空率检测及胃肠激素检测。结果:治疗后两组比较,治疗组胃排空率改善明显优于对照组,差异有显著性(P<0.05);治疗组胃动素、胃泌素均较治疗组明显升高,差异有显著性(P<0.05);生长抑素、血管活性肠肽较治疗组明显降低,差异有显著性(P<0.05)。结论:香砂六君子汤加减可改善患者胃肠动力,提高胃动素、胃泌素,降低生长抑素、血管活性肠肽,可用于功能性消化不良的治疗。
Objective:To study the effect of the Xiangsha Liujunzi decoction on gastrointestinal motility and gastrointestinal hormones in patients with functional dyspepsia.Methods:60patients with functional dyspepsia were randomly divided into the treatment group(30cases)and the control group(30cases),the treatment group was given oral administration of the Xiangsha Liujunzi decoction;30patients in the control group were given mosapride,5mg orally,3times a day,for4weeks.The detection rate of gastric emptying and gastrointestinal hormone testing were given before administration and4weeks after treatment.Results:Compared with the control group,the improvement of gastric emptying rate in the treatment group was significantly better than that in the control group(P<0.05).The levels of motilin and gastrin in the treatment group were significantly higher than those in the treatment group(P<0.05).Conclusion:The Xiangsha Liujunzi decoction could improve the gastrointestinal motility of patients and improve the motility of gastric motility and stomach,reduce somatostatin and vasoactive intestinal peptide,and it could be used to treat functional dyspepsia.
出处
《中医临床研究》
2017年第30期4-7,共4页
Clinical Journal Of Chinese Medicine
关键词
功能性消化不良
胃动力
胃肠激素
Functional dyspepsia
Gastric motility
Gastrointestinal hormones
