摘要
目的探讨乳腺癌腋窝淋巴结的超声评估价值。方法回顾性分析2016年1月~2017年4月于南京医科大学第一附属医院收治的乳腺癌患者腋窝淋巴结265例。双侧对比分析,重点观察淋巴结的皮质增厚的程度及状态,淋巴门的结构。结果超声评估腋窝正常的淋巴结132例,病理转移20例;异常的133例,病理转移77例。灵敏度79.38%、特异度66.67%、阳性预测值57.89%、阴性预测值84.85%。按皮质增厚3.0 mm分组,皮质≥3.0 mm的淋巴结转移明显,尤其是淋巴门消失的淋巴结达到100%的转移(P<0.05)。但同一皮质厚度组中均匀与不均匀在淋巴结转移上无明显差异(P>0.05),超声正常组(假阴性)较皮质≥3.0 mm淋巴结转移负荷偏低(P<0.05),与皮质<3 mm组差异不明显(P>0.05)。结论超声能够较好评估乳腺癌腋窝淋巴结的状态,皮质≥3.0 mm的淋巴结有较高的转移率。
Objective To evaluate the value of ultrasonography in diagnosis of axillary lymph node(ALN)metastasis in breast cancer.Methods A retrospective analysis of265cases of axillary lymph nodes who were diagnosed as breast cancer admitted in the first affiliated hospital of nanjing medical university from January2016to April2017were included in this study.The degree and the state of the lymph nodes of cortical thickening and the hilus structure in bilateral were analyzed.Results Nomal axillary lymph nodes were found in132cases,20with pathological metastasis.133with unnormal axillary lymph nodes,among them,77were found with pathological metastasis.The sensitivity,specificity,positive predictive value,negative predictive value were79.38%,66.67%,57.89%and84.85%respectively.These patients were then grouped according to the cortical thickening of3.0mm.As a result,patients with cortical thickness≥3.0mm had higher lymph node metastasis rate.In particular,the metastasis rate was100%in lymph node with disappearance hilus(P<0.05).But in the same group of cortical thickness uniform and non-uniform,there is no obvious difference for lymph node metastasis(P>0.05).Ultrasonic normal group(false negative)had lower metastatic nodal burden than that of cortical thickness≥3.0mm group(P<0.05).Conclusion Ultrasound can effectively evaluate axillary lymph node status in breast cancer.The metastasis rate is higher in cortical thickness≥3.0mm than that of cortical thickness<3.0mm.
作者
邓晶
李奥
周文斌
徐祎
李沁
栗翠英
苏浩波
DENG Jing;LI Ao;ZHOU Wenbing;XU Yi;LI Qin;LI Cuiying;SU Haobo(Department of Ultrasonography,The First Affiliated Hospital of Nanjing Medical University, Nanjing Jiangsu 210029, China;Department of Breast Surgery,The First Affiliated Hospital of Nanjing Medical University, Nanjing Jiangsu 210029, China;Department of Pathology, The First Affiliated Hospital of Nanjing Medical University, Nanjing Jiangsu 210029, China;Department of Ultrasound, Nanjing Hospital Affiliated to Nanjing Medical University, Nanjing Jiangsu 210006, China)
出处
《中国医疗设备》
2017年第12期72-75,共4页
China Medical Devices
基金
国家自然科学基金青年科学基金(81401427)
国家自然科学基金青年科学基金(81502299)
江苏省教育厅高校自然基金项目(14KJB320003)
关键词
乳腺癌
腋窝淋巴结
超声
皮质
breast cancer
axillary lymph node
ultrasonic
cortex
