摘要
目的:探讨复方四逆散对慢性肝炎肝纤维化的临床疗效及病理分析。方法:选择70例慢性肝炎肝纤维化患者,随机分为对照组和观察组,各35例,对照组给予秋水仙碱治疗,观察组给予复方四逆散治疗,比较两组治疗前后III型前胶原(PCIII)、透明质酸(HA)、层粘连蛋白(LN)、脯氨酸肤酶(PLD)等血清肝纤维化标志物及纤维化程度变化。结果:观察组PCIII、HA、LN水平及纤维化程度明显降低,且程度优于对照组(P<0.05)。结论:复方四逆散治疗慢性肝炎肝纤维化可有效降低纤维化程度,改善血清肝纤维化标志物水平,值得进一步研究推广。
Objective:To investigate clinical effects and pathological analysis of Fufang Sini San on hepatic fibrosis in chronic hepatitis.Methods:70cases were randomly assigned to the control group and the observation group,35cases in each.Colchicine was given to the control group;the observation group was given Fufang Sini San.Results:The levels of PCIII,HA,LN and fibrosis in the observation group were significantly decreased,lower than those in the control group(P<0.05).Conclusion:Fufang Sini San on chronic hepatitis B liver fibrosis was effective,can effectively reduce the degree of fibrosis,improve serum liver fibrosis markers level,and is worthy of further research and promotion.
出处
《中医临床研究》
2017年第29期57-58,共2页
Clinical Journal Of Chinese Medicine
关键词
复方四逆散
慢性肝炎
肝纤维化
病理
Fufang Sini San
Chronic hepatitis
Liver fibrosis
Pathology
