摘要
目的探讨美宝湿润烧伤膏、重组人表皮生长因子联合壳聚糖敷贴包扎治疗Ⅱ、Ⅲ期压疮的临床疗效。方法选取绍兴市中心医院钱清分院2015年1月～2017年1月收治的Ⅱ、Ⅲ期压疮患者120例，按随机抽签法将其分为观察组和对照组，每组60例。对照组仅给予一般处理，观察组给予美宝湿润烧伤膏、重组人表皮生长因子联合壳聚糖敷贴包扎治疗，比较2组患者的临床疗效和压疮愈合时间。结果观察组治疗总有效率（95%）高于对照组（78.33%），差异具有统计学意义（P＜0.05）。观察组Ⅱ期压疮、Ⅲ期压疮（浅度溃疡期、深度溃疡期）愈合时间均短于对照组（P＜0.05）。结论美宝湿润烧伤膏、重组人表皮生长因子联合壳聚糖敷贴包扎治疗Ⅱ、Ⅲ期压疮疗效显著，可促进创面愈合。
Objective To investigate the clinical efficacy of Moisture exposed burn ointment,recombinant human epidermal growth factor combined with chitosan patch-dressing in patients with stageⅡandⅢpressure ulcer.Methods120patients with stageⅡandⅢpressure ulcer treated in Qianqing Branch,Shaoxing Central Hospital from January2015to January2017were divided into observation group and control group according to random drawing method.The control group was given only general treatment.The observation group was treated with Moisture exposed burn ointment,recombinant human epidermal growth factor combined with chitosan patch treatment.The clinical efficacy and pressure healing time were compared between the two groups.Results The total effective rate(95%)was significantly higher in the observation group than in the control group(78.33%),the difference was statistically significant(P<0.05).The healing time of stageⅡ,Ⅲin the observation group was shorter than that of the control group(P<0.05).Conclusion Moisture exposed burn ointment,,recombinant human epidermal growth factor combined with chitosan patch dressing treatment of stageⅡ,Ⅲpressure ulcer effect is significant,can promote wound healing.
作者
周建华
沈文英
邱海江
叶国勇
ZHOU Jian-hua;SHEN Wen-ying;QIU Hai-jiang;YE Guo-yong(Department of Surgery, Qianqing Branch, Shaoxing Central Hospital, Shaoxing 312030, China;Department of Pediatrics Qianqing Branch, Shaoxing Central Hospital, Shaoxing 312030, China)
出处
《中国生化药物杂志》
CAS
2017年第11期115-116,119,共3页
Chinese Journal of Biochemical Pharmaceutics
关键词
美宝湿润烧伤膏
重组人表皮生长因子
壳聚糖
Ⅱ、Ⅲ期压疮
Moisture exposed burn ointment
recombinant human epidermal growth factor
chitosan
stageⅡ, Ⅲ pressure ulcer
