摘要
ABO血型系统的抗原在红细胞和其他正常和病理的细胞和组织的表面上表达。随着60多年前的第一个临床观察,ABO血型在肿瘤生物学的作用已经被一些研究者深入研究,ABO抗原与几种类型的肿瘤(即胰腺癌和胃癌)的发展有关得到广泛认可。然而,这种关联是否会影响恶性肿瘤的发生风险还不太确定。在这篇综述中,我们讨论了ABO血型与恶性肿瘤发生风险之间的联系。
The antigens of the ABO blood groups are expressed on red blood cell membranes as well as on the surface of several other normal and pathological cells and tissues.Following the first clinical observations more than60years ago,the role of ABO blood group in cancer biology has been intensely studied by several investigators,and it is now widely recognised that ABO antigens are associated with the risk of developing several types of tumours,namely pancreatic and gastric cancers.However,whether this association also affects the risk of cancer patients is less certain.In this narrative review,we discuss the connection between ABO blood groups and risk of malignant tumors.
出处
《科技资讯》
2017年第25期187-190,193,共5页
Science & Technology Information
基金
山东协和学院科技计划项目"ABO血型与乳腺癌发病风险的相关性研究"(课题编号:XHXY201518)
