摘要
目的探讨胰腺癌的发生与血型及丙型肝炎病毒感染的相关性,为预防与治疗胰腺癌提供理论指导依据。方法回顾性分析2012年5月-2015年4月医院肝胆胰外科收治60例胰腺癌患者临床资料,应用多变量回归方法分析ABO血型和丙型肝炎病毒感染与胰腺癌的相关性。结果胰腺癌患者中A、B、O型及AB血型所占比例分别为30.00%、28.33%、30.00%及11.67%;患者为A型血与胰腺癌的发生存在相关性,差异有统计学意义（OR1.39,95%Cl1.01~1.81,P〈0.05）;患者HCV抗体呈阳性、有糖尿病史、吸烟史、酗酒史均是导致胰腺癌的高危因素。结论 A血型和丙型肝炎病毒感染均会增加患者胰腺癌发生的风险。
OBJECTIVE To investigate the correlation of pancreatic cancer incidence to blood types and hepatitis C virus infection,so as to provide a theoretical basis for guiding the prevention and treatment of pancreatic cancer.METHODS A retrospective analysis was taken to 60 cases of pancreatic cancer patients in hepatobiliary and pancreatic surgery of our hospital from May 2012 to Apr.2015.Multivariate regression analysis was used for study the correlation between ABO blood types and hepatitis C virus infection to pancreatic cancer.RESULTS The type A,B,O and AB blood type of patients accounted for 30.00%,28.33%,30.00% and 11.67%in patients with pancreatic cancer.Patients with blood types A had correlation with the incidence of pancreatic cancer,and the difference was significant（OR=1.39,95% Cl of 1.01~1.81,P〈0.05）;HCV antibodies were positive risk factors,history of diabetes,smoking history,history of alcohol abuse were all the high risk factors leading pancreatic cancer.CONCLUSIONA-type blood and hepatitis C virus infection will increase the risk of pancreatic cancer.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2016年第19期4374-4375,4403,共3页
Chinese Journal of Nosocomiology
基金
海南省科技厅基金资助项目(201172046)
关键词
血型
丙型肝炎病毒
感染
胰腺癌
Blood
Hepatitis virus C
Infection
Pancreatic cancer
