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多索茶碱治疗支气管哮喘及临床干预观察 被引量:1

Observation of doxofylline the treatment of bronchial asthma and clinical intervention
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摘要 目的对多索茶碱治疗支气管哮喘的临床护理效果进行观察并干预。方法将浙江省医疗健康集团长兴医院2014年6月~2016年11月接收的98例支气管哮喘患者作为本次护理对象,将患者按照入院顺序分为对照组和治疗组,每组各49例,均采用多索茶碱进行治疗,对照组常规护理,治疗组在此基础上采用综合护理,对2组患者的临床效果、不良反应及治疗前后肺功能情况等进行比较。结果治疗组总有效率为89.80%,对照组总有效率为73.47%,治疗组总有效率明显优于对照组,差异具有统计学意义(P<0.05);治疗组不良反应发生率为6.12%,对照组不良反应发生率为18.37%,治疗组不良反应发生率明显优于对照组,差异具有统计学意义(P<0.05);2组患者治疗后FEV1、FFV1/FVC及PEF指标均有所改善,但治疗组明显优于对照组,差异具有统计学意义(P<0.05)。结论多索茶碱治疗支气管哮喘过程中采用综合护理具有很好的效果,且不良反应较少,值得在临床上应用推广。 Objective To observe the clinical nursing effect of doxofylline in the treatment of bronchial asthma and intervention.Methods98cases of bronchial asthma patients in our hospital from June2014to November2016received as the object of nursing,the patients were dividedinto control group and treatment group,49cases in each group,using multiple theophylline treatment,the control group was given routine care,thetreatment group on the basis of the comprehensive nursing,the clinical effects of two groups were compared before and after,adverse reactions andtreatment of pulmonary function.Results The total effective rate of treatment group was89.80%,control group total effective rate was73.47%,the total effective rate of treatment group was significantly better than the control group(P<0.05),the difference was statistically significant;thetreatment group adverse reaction rate was6.12%,the control group adverse reaction rate was18.37%,incidence of adverse reaction in treatmentgroup was significantly better than the control group(P<0.05),the difference was statistically significant;two groups of patients after treatment ofFEV1,FFV1/FVC and PEF indexes were improved,but the treatment group was significantly better than the control group(P<0.05),the differencewas statistically significant.Conclusion Doxofylline the treatment of bronchial asthma in the process of the comprehensive nursing has a goodeffect,and less adverse reactions.It is worthy of clinical application.
作者 沈卫玲 朱伟 SHEN Wei-ling;ZHU Wei(Zhejiang Province, Changxing Hospital, Medical and Health Group, Changxing 313100, China)
出处 《中国生化药物杂志》 CAS 2017年第9期252-253,255,共3页 Chinese Journal of Biochemical Pharmaceutics
关键词 多索茶碱 疗支气管哮喘 氨茶碱 临床效果 doxofylline treatment bronchial asthma aminophylline clinical effect
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