摘要
目的:本研究旨在观察应用通腑安脏汤治疗支气管哮喘伴胃肠功能障碍的临床疗效。方法:将确诊为支气管哮喘合并胃肠功能障碍的患者60例,按照区组随机化方法随机分为治疗组和对照组,对照组给予口服枸橼酸莫沙必利分散片及沙美特罗替卡松粉吸入剂治疗,治疗组给予通腑安脏汤治疗,每日1剂,两组疗程均为14天。观察两组消化道症状积分、肺功能、疗效、生活质量评估(SGRQ)[1]及随访患者3个月后再住院率。结果:与对照组相比,治疗组患者胃肠道功能障碍及生活质量明显改善(P<0.05);与对照组相比,治疗组患者肺功能无明显改善(P>0.05)。结论:应用通腑安脏汤治疗支气管哮喘合并胃肠功能障碍的疗效肯定,能显著改善支气管哮喘患者的临床症状、体征,同时改善患者的生活质量,并具有较好的安全性。
The goal of the investigation was to test and verify the therapeutic effects of Tongfu Anzang（TFAZ） decoction on bronchial asthma accompanied by Gastrointestinal Dysfunction（BAGD） patients. A total of 60 patients were diagnosed with BAGD and randomly divided into treatment group（30 cases） and control group（30 cases） adopting blocked randomization. The control group was treated with mosapride citrate dispersed tablets and salmeterol xinafoate and fluticasone propionate powder for inhalation, while the treatment group was administered by the TFAZ decoction once daily, for 14 weeks. Then the indexes, such as the GD scale, PF, therapeutic effect scale and St. George Respiratory Questionnaire（SGRQ） score were adopted to evaluate thetherapeutic effects. The readmission rate to the hospital within three months after previous discharge was another indicator. It was found that gastrointestinal symptoms and the quality of life in the treatment group were improved compared with the control group（P 〈 0.05）, while PF kept the same in the two groups（P 〉 0.05）. In conclusion, it was demonstrated that the TFAZ decoction performed well in patients with BAGD, improving their gastrointestinal symptoms and the quality of life in a safe way.
出处
《世界科学技术-中医药现代化》
2016年第5期833-838,共6页
Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology
基金
科学技术部国家"十二五"支撑计划项目(2013BAI13B02):名老中医特色治则治法传承研究
负责人:王玉光
关键词
通腑安脏汤
支气管哮喘
胃肠功能障碍
中医药治疗
胡希恕
Bronchial asthma
gastrointestinal dysfunction
traditional Chinese medicine therapy
Tongfu Anzang decoction
Hu Xishu
