摘要
[目的 ]通过对鸡H7N9流感病毒(变异株)感染临床解剖特征的描述以及H7N9流感病毒变异株来源的探讨,为今后该病的临床诊断以及防控提供借鉴。[方法 ]采用流行病学调查、临床解剖、实时荧光定量RTPCR、病毒分离测序等方法。[结果 ]病鸡外观症状与解剖症状均明显;H7、H9流感病毒核酸检测阳性;该分离株与2013年分离毒株(A/Anhui/1/2013(H7N9)的HA、NA基因核苷酸同源性分别为97.8%~97.9%、97.8%。[结论 ]鸡的感染死亡是由H7N9流感病毒(变异株)引起的;该变异株引发疫情迅猛,传染速度快,致死率高,应加强对其防控。
[Objective]To explore the clinical features of H7N9influenza virus(mutant)and the recombination possibility of H7vvN9influenza virus mutant,and to provide reference for clinical diagnosis and disease prevention and control in the future.[Methods]Epidemiological survey,clinical anatomical diagnosis,real-time quantitative RTPCR method,virus isolation sequencing were used.[Results]The appearance and anatomical symptoms of sick chicken were obvious.The results of H7and H9subtype detection were positive.The nucleotide homology of the virus isolates in HA and NA gene of A/Anhui/1/2013(H7N9)were97.9%and97.8%,respectively.[Conclusion]The infectious death of chicken was caused by H7N9influenza virus(mutant).The outbreak caused by this strain was rapid,fast and lethal,and should be strengthened and prevented.
作者
禹小芳
邹玖零
张强
黄建龙
李英明
郝知友
屈蓓蓓
周争先
罗军
尹秋元
Yu Xiaofang;Zou Jiuling;Zhang Qiang;Huang Jianlong;Li Yingming;Hao Zhiyou;Qu Beibei;Zhou Zhengxian;Luo Jun;Yin Qiuyuan(Yongzhou Animal Husbandry and Fishery Bureau,Yongzhou,Hunan 425000;Hunan Veterinary Bureau,Changsha Hunan 410000;Hunan Animal Disease Prevention and Control Center,Changsha,Hunan 410000)
出处
《中国动物检疫》
CAS
2017年第9期4-6,共3页
China Animal Health Inspection
关键词
H7N9流感病毒
变异株
临床特征
病毒重组
H7N9 influenza virus
variant strain
clinical features
viral recombination
