摘要
直肠癌是我国及世界范围内最常见的肿瘤之一,其中的高龄患者比例逐年增加。由于缺乏针对高龄患者的前瞻性循证医学证据,目前高龄患者综合治疗的标准方案尚待明确,相当比例的高龄患者并未得到最佳的综合治疗。本文将主要从老年直肠癌的流行病学、治疗模式,尤其是(新)辅助放化疗方面,系统回顾现有资料,探讨中期及局部晚期老年直肠癌的最佳治疗模式。
Rectal cancer is one of the most commonly diagnosed cancers in China and worldwide,with an increasing trend in the proportion of elderly patients. However, as the prospective evidence designedspecifically for treating this population is sparse, and the treatment algorithms for these patients becomecontroversial, it is clear that a significant percentage of elderly rectal cancer patients has been treated less thanoptimally. This paper provides overviews of the recent data on epidemiology, treatment modality, especially(neo) adjuvant chemoradiation in the treatment of older rectal cancer patients, and to discuss the optimaltreatment algorithm for the intermediate and locally advanced rectal cancer in the elderly.
作者
刘文扬
金晶
Liu Wenyang;Jin Jing(Department of Radiotherapy, Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China)
出处
《中华结直肠疾病电子杂志》
2016年第1期21-26,共6页
Chinese Journal of Colorectal Diseases(Electronic Edition)
基金
国家自然科学基金资助项目(81272510)
关键词
直肠肿瘤
治疗
老年人
Rectal neoplasms
Therapy
Elderly
