摘要
Chemical studies on nine Salvia species yielded various polyphenolic acids. Eleven of them were depsides of R (+) β (3,4 dihydroxyphenyl) lactic acid and a caffeic acid derivative or caffeic acid dimer. Except the two known depsides, rosmarinic acid and lithospermic acid, this type of depsides has not been isolated from other plant materials before, so they were named salvianolic acid A, B, C, D, E, H, I, J and isosalvianolic acid C. Salvianolic acid F, G and przewalskinic acid A were new polyphenolic acids. Pharmacological studies of these polyphenolic acids showed potent antioxidant activities. The effects of these components in protecting against brain and heart damage have been studied.
经化学研究，自９种鼠尾草属植物中获得各种多酚酸类化合物，其中１１个成分为缩酚酸类化合物，其化学结构是由Ｒ（＋）β（３，４二羟基苯基）乳酸和咖啡酸的衍生物或咖啡酸的二聚物酯化而成的。除了迷迭香酸和紫草酸以外，此类缩酚酸未曾从其它植物中分离得到，因此命名其为丹酚酸Ａ，Ｂ，Ｃ，Ｄ，Ｅ，Ｈ，Ｉ，Ｊ和异丹酚酸Ｃ。丹酚酸Ｆ，Ｇ和甘肃鼠尾草酸Ａ为新的多酚酸类化合物。药理实验结果说明这些多酚酸具有很强的抗氧化活性。对这些化合物的心、脑损伤保护作用亦进行了研究。
