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腹腔镜与开腹直肠癌的老年患者术后CRP、TNF-α、IL-6的对比研究 被引量:2

A Comparative Study on Postoperative CRP,TNF-and IL-6 Levels of Elderly Patients with Carcinoma of the Rectun Treated with 0Peritoneoscope and Laparotomy
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摘要 目的比较腹腔镜与开腹直肠癌根治术对老年患者免疫功能的影响。方法 40例老年直肠癌患者,随机分配到腹腔镜组及开腹组,各组均为20例,分别于手术前1d,术后第1、3、7d抽取外周血测定并比较患者的CRP、TNF-α、IL-6水平结果。结果术前1d两组患者血清CRP、TNF-α及IL-6水平比较差异均无统计学意义(P>0.05),而手术后第1、3、7d炎性指标水平均低于开腹组,比较差异均具有统计学意义(P<0.05)。结论腹腔镜直肠癌根治术对老年患者免疫功能的影响较开腹手术小,更有利于老年直肠癌患者的恢复。 Objective compare the impact of radical resection of carcinoma of the rectum with Laparoscopic and laparotomy on the immune function of elderly patients. Method 40 elderly patients with carcinoma of the rectum were randomly assigned to a group an a laparotomic group,20 in each group. Peripheral blood of the groups of patients was sampled 1 day postoperative,respectively,where the CRP,TNF- and IL- 6 Levels were measured and compared. Results : there was not statistical significance in the difference in the CRP,TNF-and IL- 6 Levels the samples,1 day preoperative,in the two groups of patients(P > 0. 05),while the inflammatory index levels,1 day,3days an 7 days postoperative,in the peritoneoscopic group were lower than those in the laparotomic group,which was statistically significant(P < 0. 05). Conclusions : The impact of the radical resection of caricinoma of the rectum with peritoneoscope on the immune function of elderly paitents is smaller than that with laparotomy,thus the peritoneoscopic treatment is more conductive to the recovery of elderly parients with carcinoma of the rectum.
出处 《结直肠肛门外科》 2016年第S1期140-140,共1页 Journal of Colorectal & Anal Surgery
关键词 腹腔镜 开腹 老年患者 直肠癌根治术 免疫功能 Peritoneoscope Laparotpmy Elderly Patients Radical resction of Carcinoma of the rectum Immune Function
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