摘要
目的 :观察中药“清痹方”合双氯芬酸钠联合治疗类风湿性关节炎的疗效和不良反应。方法 :6 0例患者随机分为治疗组和对照组。两组均维持常规的甲氨喋呤 7.5mg ,每周 1次治疗。对照组服用双氯芬酸钠 2 5mg ,每日 3次 ;治疗组除服用双氯芬酸钠 2 5mg ,每日 3次外 ,加服“清痹方” ,每日 2剂。观察治疗后的临床疗效、实验室检查和不良反应。结果 :对照组总有效率为 76 .7% ,治疗组为 86 .7% ,不良反应对照组发生 7例 ,治疗组发生 2例。结论 :“清痹方”合双氯芬酸钠联合治疗类风湿性关节炎疗效佳 ,不良反应少。
Objective: To observe the efficacy and side effect of Qingbifang a traditonal Chinese medicine, combined with diclofenac sodium in the treatment of rheumatic arthritis. Method: 60 patients were divided randomly in to the trial group and the control group. All the patients were given methotexate (MTX) 7.5mg 9w routinely. Patients in the control group were given diclofenac sodium 25 mg t.i.d, while patients in the trial group were given Qingbifang B.i.d in addition. Items including clinical efficacy, Laboratory tests and side effects were analyzed afterwares. Results: The total effective rates were 76.7% and 86.7% in the control and trial group respectively. As for side effect, 7 cases were reported in the control group while only 2 cases were reported in the trial group. Conclusion: The combined treatment of Qingbifang and diclofenac sodium is effective and sape in the chemotherapy of rheumatic arthritis.
出处
《中国临床医学》
2002年第4期443-444,共2页
Chinese Journal of Clinical Medicine
