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依托考昔治疗急性重度痛风性关节炎的疗效研究 被引量:11

Efficacy Study of Etoricoxib in the Treatment of Acute Severe Gouty Arthritis
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摘要 目的分析研究依托考昔对急性重度痛风性关节炎患者的临床治疗效果。方法选取136例急性重度痛风性关节炎患者,随机将其分为对照组和观察组,每组68例。对照组给予双氯芬酸钠进行治疗,观察组给予依托考昔进行治疗。结果与对照组相比,观察组患者的临床症状具有明显的改善,对比差异具有显著性意义(P<0.05)。对照组患者的治疗总有效率(79.4%)显著低于观察组患者(95.6%);且观察组不良反应发生数为3例,对照组为9例,差异均具有统计学意义(P<0.05)。结论采用依托考昔进行急性痛风性关节炎的治疗具有良好的临床疗效,且病症改善明显,不良反应少,值得在临床推广使用。 Objective To analyze the effect of etoricoxib in the treatment of acute severe gouty arthritis. Methods 136 cases of acute severe gouty arthritis were selected and randomly divided into control group and observation group with 68 cases each. Control group received diclofenac treatment, while observation group received etoricoxib treatment. Results Compared with control group, the clinical symptoms in observation group had significantly improved, the difference was significant(P 〈0.05). The total effective rate of control group(79.4%) was significantly lower than that of observation group(95.6%); and the number of adverse reactions in observation group was 3 cases, and that in control group was 9 cases, the differences was statistically significant(P 〈0.05). Conclusion Applying etoricoxib for acute gouty arthritis has a good clinical effect, and improves symptoms significantly, with fewer adverse reactions, which is worth in clinical use.
作者 潘奇 陈黔
机构地区 贵州省骨科医院
出处 《中国医药指南》 2016年第8期107-108,共2页 Guide of China Medicine
关键词 依托考昔 急性重度痛风性关节炎 临床疗效分析 Etoricoxib Acute severe gouty arthritis Clinical effect analysis
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