摘要
用抗θ血清处理带B_(16)黑色素瘤的C_(57)BL/6小鼠后,肺转移数增多,其脾林巴细胞对ConA的反应性降低。如抗θ血清处理的带瘤鼠用胸腺肽后,则肺转移数和T淋巴细胞的增殖反应均有明显的改变,肺转移数减少,脾脏T淋巴细胞对ConA的反应性增强。
The effect of thymic peptide (TP) on tumor metastasis and Lymphocyte proliferation in C57BL/6 mice treated with anti-theta serum was studied. The results showed the nunber of pulmonary metastatic colonies was increased and the respone of spleen lymphocytes tO Con A. measured by ~3H-thymidine incorporation was suppressed significantly as compared with Control. Treating the mice with TP could decrease the nunber of pulmonary metastatic colonies and enhance lymphocyte transformation as compared with those only treated with anti-theta serum.
出处
《肿瘤防治研究》
CAS
CSCD
北大核心
1991年第4期202-205,共4页
Cancer Research on Prevention and Treatment
关键词
胸腺肽
肿瘤
转移
T细胞
Thymic peptide
BI6-melanoma
C57BL/6 mice
T-Lymphocyte
Metastasis
