摘要
目的探究正电子发射-计算机断层扫描显像(PET-CT)在弥漫大B细胞淋巴瘤(DLBCL)诊治中的应用。方法回顾性分析86例DLBCL患者临床资料,所有患者均于治疗前后接受PET-CT检查,分析PET-CT对DLBCL分期的诊断价值及治疗前后患者PET-CT影像特征;根据治疗效果分为完全缓解组(CR组,n=35)、部分缓解组(PR组,n=33)、疾病稳定组(SD组,n=8)、进展组(PD组,n=10),比较四组患者治疗前后标准化摄取最大值变化率(ΔSUV_(max))、病灶直径水平差异。结果 PET-CT对DLBCL分期诊断准确率为91.9%(79/86)。治疗前后患者PET-CT影像特征均有不同程度变化,四组ΔSUV_(max)水平比较差异有统计学意义(P<0.05);四组病灶直径比较差异无统计学意义(P>0.05)。结论 PET-CT在DLBCL诊治过程中可提供较可靠的影像学依据,有较高应用价值。
Objective To explore the application of positron emission tomographycomputed tomography(PET-CT)in the diagnosis and treatment of diffuse large B-cell lymphoma(DLBCL).Methods The clinical data of 86 DLBCL patients were analyzed retrospectively.All patients were given PET-CT examination before and after treatment,and the diagnostic value of PET-CT in the DLBCL staging and the PET-CT imaging features were analyzed.According to the treatment effect,the patients were divided into complete remission group(CR group,n=35),partial remission group(PR group,n=33),disease stabilization group(SD group,n=8)and progression group(PD group,n=10).The maximum change rate of standardized uptake value(ΔSUVmax)and the lesion diameter were compared before and after treatment among four groups.Results The diagnostic accuracy of PET-CT for DLBCL staging was 91.9%(79/86).The PET-CT imaging features were changed in different degrees before and after treatment,and there were significant differences in theΔSUVmax among four groups(P<0.05).There was no significant difference in lesion diameter among four groups(P>0.05).Conclusion PETCT can provide reliable imaging basis in the diagnosis and treatment of DLBCL,and has high clinical value.
作者
王万里
董志辉
郭淑利
付立武
魏珍星
张海鸽
WANG Wan-li;DONG Zhi-hui;GUO Shu-li(Department of Blood Internal Medicine,Luoyang center hospital affiliated to zhengzhou university,luoyang 471003,Henan Province,China)
出处
《中国CT和MRI杂志》
2019年第3期146-149,共4页
Chinese Journal of CT and MRI
