摘要
20 0只 AA肉鸡随机等分为对照组 (C)和试验组 (T) ,C组和 14日龄前 T组鸡按常规饲养。 T组自 14日龄起舍温从 2 5℃起每天降 1～ 2℃逐渐降至 12℃ ,同时在日粮中按 1.5 m g/ kg的剂量添加三碘甲腺原氨酸 (T3 )以诱发肺动脉高压综合征 (PHS)。分别于 2 1、2 8、35、42、49日龄测定 2组肉鸡平均肺动脉压 (m PAP)、红细胞压积 (PCV)、右心全心比 (RV/ TV)、血浆内皮素 (ET- 1)及一氧化氮 (NO)水平 ,同时记录 PHS发病率。结果显示 ,试验组肉鸡 m PAP升高 ,PHS发病率增加 ;PCV、RV/ TV及血浆 ET- 1水平与对照组相比都显著升高 (P<0 .0 1) ;m PAP变化与血浆 ET- 1含量变化之间存在显著正相关 ,2组间血浆 NO水平无显著差异 (P>0 .0 5 ) ,但都出现随日龄增加血浆 NO水平升高的现象。
Two hundred AA broilers were divided randomly into control(Group C) and low temperature treated groups(Group T) evenly.Broilers in group T before 14 days of age and group C were subjected to a normal feeding program.In group T,broilers were subjected to a step down temperature program of 1-2℃ per day,starting from 25℃(day 14) down to 12℃,and then maintained at this ambient temperature until 7 weeks of age.At same time 3,3,5-triiodothyronine(T 3) was added with concentration 1.5 mg/kg in the diet of group T in order to induce pulmonary hypertension.To the more extent,mean pulmonary arterial pressure(mPAP),PCV,RV/TV,plasma endothelin-1(ET-1) and nitric oxide(NO) were determined on day 21,28,35,42 and 49,and ascites incidence was recorded every week.It was found that mPAP,PCV,RV/TV,plasma ET-1 and ascites incidence of broilers in group T were significantly higher than those of broilers in group C;plasma ET-1 and mPAP had a significant correlation(r=0.726).No significant difference was found between plasma NO of two groups,but the trend of increment of plasma NO with the days delaying was observed.
出处
《中国兽医学报》
CAS
CSCD
北大核心
2002年第5期509-511,共3页
Chinese Journal of Veterinary Science
基金
国家自然科学基金资助项目 ( 399970 5 6 8)
高校博士点基金资助项目 ( B980 0 0 2 )
江苏省"九五"农业重点攻关项目( BE96 488)
关键词
T3
肉鸡
内皮素
一氧化氮
肺动脉压
生态环境
温度
broiler
pulmonary hypertension syndrome(PHS)
pulmonary arterial pressure(PAP)
cold
endothelin-1
nitric oxide
