摘要
目的探讨同型半胱氨酸水平对老年H型高血压冠心病患者冠状动脉狭窄程度与的影响。方法选取2016年1月至2017年6月111例老年H型高血压冠心病患者,依据同型半胱氨酸水平分组,对照组55例同型半胱氨酸水平<10μmol/L,观察组56例同型半胱氨酸水平≥10μmol/L,对比两组患者冠状动脉狭窄程度。结果观察组Gensini积分及重度狭窄发生率均低于对照组,轻度狭窄发生率高于对照组患者(P <0. 05),两组患者中度狭窄发生率基本相当(P> 0. 05)。结论同型半胱氨酸水平对于冠状动脉狭窄病变程度有一定判断价值,临床治疗H型老年高血压冠心病患者时,建议降压同时,尽可能降低同型半胱氨酸水平,减少血管损伤,促进疾病快速转归。
Objective To investigate the relationship between the degree of coronary artery stenosis and the level of homocysteine in elderly patients with H-type hypertension. Methods A total of111 elderly patients with H-type hypertension coronary heart disease were divided into two groups according to homocysteine level. Fifty-five cases with homocysteine level 10 μmol/L in the control group,and 56 cases with homocysteine level ≥10 μmol/L in observation group,the degree of coronary artery stenosis in the two groups were compared. Results The incidence of Gensini score and severe stenosis was lower in the observation group than those in the control group（ P〈 0. 05）. The incidence of mild stenosis was higher than that in the control group（ P〈 0. 05）. The incidence of moderate stenosis was similar in the two groups（ P〉 0. 05）. Conclusions The level of homocysteine has certain value for the degree of coronary artery stenosis. When clinically treating patients with H-type elderly patients with hypertension and coronary heart disease, it is recommended to reduce blood pressure, reduce homocysteine level as much as possible,reduce vascular injury and promote the rapid returning of the disease.
作者
原建华
Yuan Jianhua(Department of Cardiology,the People＇s Hospital of Hebi,Hebi 458030,China)
出处
《临床医学》
CAS
2018年第11期8-9,14,共3页
Clinical Medicine
关键词
同型半胱氨酸
老年
H型高血压
冠心病
冠状动脉狭窄
Homocysteine
Old age
H-type hypertension
Coronary heart disease
Coronary artery stenosis
